Papers - KUDO Naomi
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Effects of perfluorinated fatty acids with different carbon chain length on fatty acid profiles of hepatic lipids in mice. Reviewed
Kudo, N., Yamazaki, T., Sakamoto, T., Sunaga, K., Tsuda, T., Mitsumoto, A. and Kawashima, Y.
Biological and Pharmaceutical Bulletin 34 ( 6 ) 856 - 864 2011.03
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal) Publisher：The Pharmaceutical Society of Japan
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Clofibric acid increases the formation of oleic acid in endoplasmic reticulum of the liver of rats. Reviewed
Hirose, A., Yamazaki, T., Sakamoto, T., Sunaga, K., Tsuda, T., Mitsumoto, A., Kudo, N. and Kawashima, Y.
Journal of Pharmacological Sciences 116 362 - 372 2011
Language：English Publishing type：Research paper (scientific journal) Publisher：Japanese Pharmacological Society
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Pharamacokinetics of nateglinide enantiomers and their metabolites in Goto-Kakizaki rats, a model of type 2 diabetes mellitus Reviewed
Masafumi Tamura, Sachiko Shiba, Naomi Kudo, Yoichi Kawashima
Chirality 22 92 - 98 2010.02
Language：English Publishing type：Research paper (scientific journal)
経口投入病薬ナテグリニドおよびそのエナンチオマーについて、2型糖尿病モデルラットにおける動態解析を行った。ナテグリニドLエナンチオマーは、糖尿病ラットにおいて全身クリアランスおよび分布容積がナテグリニドよりも大きいことを明らかにした。
DOI： 10.1002
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Peroxisome proliferators attenuate free arachidonic acid pool in the kidney through inducing lysophospholipid acyltransferases Reviewed
Tohru Yamazaki, Akihiko Hiroshe, Takeshi Sakamoto, Mari Okazaki, Atsushi Mitsumoto, Naomi Kudo, Yoichi Kawashima
Journal of Pharmacologycal Sciences 111 201 - 210 2009.12
Language：English Publishing type：Research paper (scientific journal)
ペルオキシソーム増殖剤であるクロフィブリン酸、フタル酸エステルなどをラットに摂取させると、肝臓と腎臓において数種類のリゾリン脂質アシルトランスフェラーゼが誘導された。この誘導はmRNAレベルの上昇を友経っており、転写活性化によると考えられる。結果として腎臓における遊離アラキドン酸レベルの減少がおこるものと考えられる。
DOI： 10.1254
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Efficacy of urine bile acid as a non-invasive indicator of liver damage in rats Reviewed
Hiroshi Kawai, Naomi Kudo, Yoichi Kawasima, Atsushi Mitsumoto
The Journal of Toxicological Sciences 34 ( 1 ) 27 - 38 2009.01
Language：English Publishing type：Research paper (scientific journal)
thioacetamide で誘発した肝障害モデルラットにおいて、血清中の肝障害マーカーであるalkaline phosphatase などと尿中のビリルビン濃度に高い相関が認められることから、非侵襲のマーカーとして有用であることを見出した。
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Manifesatation of psychiatric behaviors in a mouse model of griseofulvin-induced hepatic injury Reviewed
Yoko Sato, Reiko Iwadate, Yukino Watanabe, Hiroshi Kawai, Naomi Kudo, Yoichi Kawasima, Atsushi Mitsumoto
The Journal of Toxicological Sciences 33 ( 5 ) 599 - 608 2008.12
Language：English Publishing type：Research paper (scientific journal)
Griseofulvinを摂取させて誘発した肝ポルフィリン症モデルマウスにおいて、用量および摂取期間依存的な不安症やうつ状態が認められたことから、ヒトのポルフィリン症における精神神経症状の発症メカニズム解明のための有益なツールとなることを示した。
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Effects of supplemented diacylglycerol rich in docosahexaenoic acid on serum triacylglycerol in a diet-induced hyperlipidemic model of rats are essentially equivalent to those of triacylglycerol rich in docosahexaenoic acid. Reviewed
1. Tamai, T., Murota, I., Maruyama, K., Baba, T., Toyama, T., Watanabe, N., Kudo, N. and Kawashima, Y.
Biol Pharm Bull. 30 ( 12 ) 2381 - 2388 2007.12
Language：English Publishing type：Research paper (scientific journal)
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Tissue distribution and subcellular distribution of peprfluorooctanoic acid at low dose are different from those at high dose in rats."jointly worked" Reviewed
Kudo N.,Sakai A.,Mitsumoto A.,Hibino Y.,Tsuda T.,Kawashima, Y.
Biol. Pharm. Bull. 30 ( 8 ) 1535 - 1540 2007.08
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
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Reducing effect of matrix metalloproteinase inhibitors on serum triacylglycerol in streptozotocin-induced diabetic rats and Zucker fa/fa rats."jointly worked" Reviewed
Morikawa T.,Kudo N.,Toyama T.,Kawashima Y.
Biol. Pharm. Bull. 30 ( 8 ) 1461 - 1467 2007.08
Authorship：Second author Language：English Publishing type：Research paper (scientific journal)
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Effects of pioglitazone on stearoyl-CoA desaturase in obese Zucker fa/fa rats."jointly worked" Reviewed
Toyama T.,Kudo N.,Hibino Y.,Mitsumoto A.,Nishikawa M.,Kawashima K.
J. Pharm. Sci. 104 ( 2 ) 137 - 145 2007.06
Authorship：Second author Language：English Publishing type：Research paper (scientific journal)
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Stearoyl-CoA desaturase activity is elevated by the suppression of its degradation by clofibric acid in the liver of rats."jointly worked" Reviewed
Toyama T.,Kudo N.,Mitsumoto A.,Hibino Y.,Tsuda, T.
J. Pharm. Sci. 103 ( 4 ) 383 - 390 2007.04
Authorship：Second author Language：English Publishing type：Research paper (scientific journal)
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Rat organic anion transporter 3 and organic anion transporting polypeptide 1 mediate perfluorooctanoic acid transport"jointly worked" Reviewed
Katakura M.,Kudo N.,Tsuda T.,Hibino Y.,Mitsumoto A.,Kawashima, Y.
J. Health Science 53 ( 1 ) 77 - 83 2007.01
Authorship：Second author Language：English Publishing type：Research paper (scientific journal)
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Responses of the liver to perfluorinated fatty acids with different carbon chain length in male and female mice:In relation to induction of hepatomegaly, peroxisomal .-oxidation and microsomal 1-acylglycerophosphocholine acyltransferase."jointly worked" Reviewed
Kudo N.,Suzuki- Nakajima E.,Mitsumoto A.,Kawashima Y.
Biol. Pharm. Bull. 29 ( 9 ) 1952 - 1957 2006.09
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
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Effect of 8-2 fluorotelomer alcohol on oleic acid formation in the liver of rats."jointly worked" Reviewed
Iwase Y.,Kudo N.,Toyama T.,Tamura M.,Mitsumoto A.,Kawashima Y.
Biol. Pharm. Bull. 28 ( 8 ) 1740 - 1746 2006.08
Language：English Publishing type：Research paper (scientific journal)
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Studies on the mechanisms for the accumulation of perfluorinated fatty acids and related compounds Invited
Kudo, N
22 21 - 26 2006.08
Authorship：Lead author Language：Japanese Publishing type：Research paper (scientific journal)
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Temperature rhythm reentrains faster than locomotor rhythm after a light phase shift."jointly worked" Reviewed
Sato Y.,Kawai H.,Kudo N.,Kawashima Y.,Mitsumoto, A.
Physiology and Behavior 88 ( 4-5 ) 404 - 410 2006.07
Language：English Publishing type：Research paper (scientific journal)
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Time-restricted feeding entrains daily rhythms of energy metabolism in mice."jointly worked" Reviewed
Sato Y.,Kawai H.,Kudo N.,Kawashima Y.,Mitsumoto A.
Am. J. Physiol., Regul., Integr., Comp. Physiol. 290 ( 5 ) 1276 - 1283 2006.02
Language：English Publishing type：Research paper (scientific journal)
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Induction of hepatic peroxisome proliferation by 8-2 telomer alcohol feeding in mice: Formation of perfluorooctanoic acid."jointly worked" Reviewed
Kudo N.,Iwase Y.,Okayachi H.,Yamakawa Y.
Toxicol. Sci. 86 ( 2 ) 231 - 238 2005.08
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
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Regulation of palmitoyl-CoA chain elongation by clofibric acid in the liver of Zucker fa/fa rats."jointly worked" Reviewed
Toyama T.,Kudo N.,Mitsumoto A.,Kawashima Y.
Lipids 40 ( 5 ) 463 - 470 2005.05
Authorship：Second author Language：English Publishing type：Research paper (scientific journal)
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Effects of perfluorocarboxylic acids on the activities of acyl-CoA elongations in vivo and in vitro."jointly worked" Reviewed
ToyamaT.,Kudo N.,Mitsumoto A.,Kawashima Y.
Chemico-Biol. Interact. 150 ( 2 ) 189 - 198 2004.11
Authorship：Second author Language：English Publishing type：Research paper (scientific journal)