Papers - TODO Hiroaki
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Verification of nanoparticle formation, skin permeation, and apoptosis using nobiletin as a methoxyflavonoid derivative Reviewed
Yutaka Inoue, Moe Ishizawa, Shoko Itakura, Takashi Tanikawa, Hiroaki Todo
AAPS Open 8 2022.11
Language：English Publishing type：Research paper (scientific journal)
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A Mathematical Approach Using Strat-M® to Predict the Percutaneous Absorption of Chemicals under Finite Dose Conditions. Reviewed
Kunita R, Nishijima T, Todo H, Sugibayashi K, Sakaguchi H.
Pharmaceutics 14 ( 7 ) 2022.06
Language：English Publishing type：Research paper (scientific journal)
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Preparation, Characterization, Solubility, and Antioxidant Capacity of Ellagic Acid-Urea Complex Reviewed
Sakurai H, Suzuki M, Itakura S, Todo H, Arce F Jr, See GL, Tanikawa T, Inoue Y.
Materials 15 ( 8 ) 2022.04
Language：English
DOI： 10.3390/ma15082836.
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Self-Assembled Structure of α-Isostearyl Glyceryl Ether Affects Skin Permeability-a Lamellar with 70-nm Spaces and L3 Phase Enhanced the Transdermal Delivery of a Hydrophilic Model Drug Reviewed
Tomohiko Sano, Akie Okada, Kazunori Kawasaki, Takuji Kume, Minoru Fukui, Hiroaki Todo, Kenji Sugibayashi
AAPS PharmSciTech 23 ( 8 ) 2022.04
Language：English Publishing type：Research paper (scientific journal)
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A Pilot Study of Transdermal Application of Diphenhydramine to the Nasal Ala in Patients with Allergic Rhinitis and Asthma. Reviewed
Kamimura M, Inui T, Mouri A, Todo H, Sugibayashi K, Asano K.
Tokai J Exp Clin Med. 47 ( 4 ) 2022.04
Language：English Publishing type：Research paper (scientific journal)
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A step-by-step approach for assessing acute oral toxicity without animal testing for additives of quasi-drugs and cosmetic ingredients. Reviewed
Kojima H, Nakada T, Yagami A, Todo H, Nishimura J, Yagi M, Yamamoto K, Sugiyama M, Ikarashi Y, Sakaguchi H, Yamaguchi M, Hirota M, Aizawa S, Nakagawa S, Hagino S, Hatao M.
Curr Res Toxicol. 4 2022.04
Language：English Publishing type：Research paper (scientific journal)
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Remote-controllable dosage management through a wearable iontophoretic patch utilizing a cell phone Reviewed
Mori K, Yamazaki K, Takei C, Oshizaka T, Takeuchi I, Miyaji K, Todo H, Itakura S, Sugibayashi K.
Journal of controlled release 355 2022.04
Language：English Publishing type：Research paper (scientific journal)
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Intraperitoneal administration of nanoparticles containing tocopheryl succinate prevents peritoneal dissemination Reviewed
Hama S, Nishi T, Isono E, Itakura S, Yoshikawa Y, Nishimoto A, Suzuki S, Kirimura N, Todo H, Kogure K.
Cancer Sci 113 ( 5 ) 1779 - 1788 2022.04
Language：English
DOI： 10.1111/cas.15321
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Estimation of skin absorption of chemicals with Fick's diffusion model Reviewed
Hiroaki Todo
Nihon Yakurigaku Zasshi 157 ( 5 ) 335 - 339 2022.04
Authorship：Lead author, Corresponding author Language：Japanese Publishing type：Research paper (scientific journal)
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Development of Self-Administered Formulation to Improve the Bioavailability of Leuprorelin Acetate. Reviewed
Okada A, Niki R, Inoue Y, Tomita J, Todo H, Itakura S, Sugibayashi K.
Pharmaceutics 14 ( 4 ) 2022.04
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
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Enhancement of skin permeation of fluorescein isothiocyanate-dextran 4 kDa (FD4) and insulin by thermalporation Reviewed
Ono N, Iibuchi T, Todo H, Itakura S, Adachi H, Sugibayashi K.
Eur J Pharm Sci . 2022.03
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
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Estimation of skin absorption of chemicals with Fick's diffusion model
Hiroaki Todo
Nihon yakurigaku zasshi 157 ( 5 ) 335 - 339 2022.01
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Development of nanoparticles derived from corn as mass producible bionanoparticles with anticancer activity. Reviewed
Daisuke Sasaki, Kosuke Kusamori, Yukiya Takayama, Shoko Itakura, Hiroaki Todo, Makiya Nishikawa
Scientific reports 2021.11
Language：English Publishing type：Research paper (scientific journal)
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Validation study of a new reconstructed human epidermis model EPiTRI for in vitro skin irritation test according to OECD guidelines. Reviewed International coauthorship
Chih-Ching Liao, Cheng-Yi Wu, Meng-Hsueh Lin, Feng-Koo Hsieh, Lih-Tao Hsu, Shiun-Yin Chang, Kuan-Jen Chen, Hui-Ting Huang, Hui-Chun Hsu, Chiu-Hsing Lin, Pei-Ju Lin, Huey-Min Lai, Hajime Kojima, Hiroaki Todo, Sung-Jan Lin, Jih-Heng Li, Wannhsin Chen
Toxicology in vitro 2021.09
Language：English Publishing type：Research paper (scientific journal)
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Effect of Rubbing Application on the Skin Permeation of Active Ingredients from Lotion and Cream Reviewed International journal
Abe A, Suzuki H, Amagai S, Saito M, Itakura S, Todo H, Sugibayashi K.
Chem Pharm Bull 69 ( 8 ) 806 - 810 2021.04
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
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Design and Optimization of Scored Tablets with Concave Surface and Application of Bayesian Estimation for Solving Scaleup Problem. Reviewed
Hiroki Katayama, Yoshiharu Maeda, Tsubasa Sato, Asami Mogi, Shoko Itakura, Hiroaki Todo, Kenji Sugibayashi, Kozo Takayama
Chemical & pharmaceutical bulletin 69 ( 11 ) 2021.04
Language：English Publishing type：Research paper (scientific journal)
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Effect of Iontophoresis on the Intradermal Migration Rate of Medium Molecular Weight Drugs Reviewed International journal
Kenji Sugibayashi, Mika Futaki , Miyu Hashimoto, Asuka Fukuhara , Kengo Matsumoto, Takeshi Oshizaka , Shoko Itakura , Hiroaki Todo
Chem Pharm Bull (Tokyo) 69 639 - 645 2021.04
Language：English Publishing type：Research paper (scientific journal)
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Improvement of Skin Permeation of Caffeine, a Hydrophilic Drug, by the Application of Water Droplets Provided by a Novel Humidifier Device. Reviewed International journal
Todo H, Hasegawa Y, Okada A, Itakura S, Sugibayashi K.
Chem Pharm Bull 69 ( 8 ) 674 - 680 2021.04
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
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ナノ粒子の皮膚浸透性と安全性
木村 恵理子 , 藤堂 浩明 , 杉林 堅次
薬学雑誌 2021.03
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Application of diphenydramine ointment to the eyelids for allergic conjunctivitis Reviewed International journal
Mitsuhiro Kamimura, Takako Ohnish, Hisao Terada, Atsuto Mouri, Takahiro Naoi, Hiroaki Todo, Kenji Sugibayashi
IBEROAMERICAN JOURNAL OF MEDICINE 44 - 50 2021.01
Language：English Publishing type：Research paper (scientific journal)