KOBATA Kenji

写真a

Affiliation

Faculty of Pharmaceutical Sciences Department of Pharmaceutical Technochemistry

Title

Professor

External Link

Degree 【 display / non-display

  • 博士(農学) ( 1995.03   岐阜大学 )

Research Areas 【 display / non-display

  • Life Science / Food sciences

From School 【 display / non-display

  • Shinshu University   Faculty of Agriculture   Graduated

    - 1990.03

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    Country:Japan

From Graduate School 【 display / non-display

  • Gifu University   Graduate School, Division of Agricltural Sciences   Doctor's Course   Completed

    - 1995.03

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    Country:Japan

  • Shinshu University   Graduate School, Division of Agriculture   Master's Course   Completed

    - 1992.03

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    Country:Japan

Employment Record in Research 【 display / non-display

  • Josai University   Faculty of Pharmaceutical Sciences   Department of Pharmaceutical Technochemistry   Professor

    2015.04

  • Josai University   Faculty of Pharmaceutical Sciences   Department of Pharmaceutical Technochemistry   Associate Professor

    2007.04 - 2015.03

Professional Memberships 【 display / non-display

  • 日本薬学会

    2008.04

  • 日本栄養・食糧学会

    1996.12

  • 日本農芸化学会

    1990.12

 

Research Career 【 display / non-display

  • 食品成分の生体調節機能に関する研究

    (not selected)  

    Project Year: 2007.04  -   

  • トウガラシ辛味成分の生合成に関する研究

    Cooperative Research  

    Project Year: 2007.04  -   

  • カプサイシン受容体に作用する成分の研究

    Cooperative Research  

    Project Year: 1997.04  -  2010.03 

  • トウガラシ成分の研究

    Cooperative Research  

    Project Year: 1996.04  -   

  • Enzymatic synthesis of capsaicin analogs

    Cooperative Research  

    Project Year: 1995.04  -  1999.03 

Papers 【 display / non-display

  • Coffee ingredients, hydropuinone, pyrocatechol, and 4-ethylcatechol exhibit anti-inflammatory activity through inhibiting NF-κB and activating Nrf2. Reviewed

    Megumi Funakoshi-Tago, Mari Matsutaka, Shingo Hokimoto, Kenji Kobata, Kenji Tago, and Hiroomi Tamura

    Journal of Functional Foods   90   104980   2022

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Spermine suppresses adipocyte differentiation and exerts anti-obesity effects in vitro and in vivo. Reviewed

    23   11818   2022

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    Language:English  

  • Vanillin reduction in the biosynthetic pathway of capsiate, a non-pungent component of Capsicum fruits, is catalyzed by cinnamyl alcohol dehydrogenase. Reviewed

    Kaori Sano, Yuya Uzawa, Itsuki Kaneshima, Saika Nakasato, Masashi Hashimoto, Yoshiyuki Tanaka, Sachie Nakatani, and Kenji Kobata

    Scientific Reports   12   12384   2022

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

  • Effect of urolithin A on Japanese cedar allergic rhinitis in mice. Reviewed

    Nobuo Morishita, Sachie Nakatani, Hiromu Shimizu, Kazumi Hayashi, Katsuhiro Ishikawa, Natsuko Ozawa, Masatake Kudoh, Yuichi Ukawa, and Kenji Kobata

    Functional Food Research   18   57 - 64   2022

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    Authorship:Last author, Corresponding author   Language:Japanese   Publishing type:Research paper (scientific journal)  

  • Pyrocatechol, a component of coffee, suppresses LPS-induced inflammatory responses by inhibiting NF-κB and activating Nrf2. Reviewed International journal

    Megumi Funakoshi-Tago, Kenji Kobata, and Hiroomi Tamura

    Scientific Reports   10   2584   2020

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    Language:English   Publishing type:Research paper (scientific journal)  

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Books and Other Publications 【 display / non-display

  • 機能性食品開発のための初期評価試験プロトコール集

    中谷祥恵,真野博,古旗賢二( Role: Joint author)

    シーエムシー出版  2017 

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    Language:Japanese   Book type:Scholarly book

  • 食品機能成分の吸収・代謝機構

    宮澤陽夫 監修( Role: Contributor)

    シーエムシー出版  2013 

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    Language:Japanese   Book type:Scholarly book

  • スパイス・ハーブの機能と最新応用技術(共著)

    古旗賢二( Role: Joint author)

    シーエムシー出版  2011.01  ( ISBN:9784781303000

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    Language:Japanese   Book type:Scholarly book

  • スパイスなんでも小辞典

    日本香辛料研究会( Role: Contributor)

    講談社  2011 

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    Language:Japanese   Book type:Scholarly book

  • Nutrigenomics and Proteomics in Health and Disease: Food Factors and Gene Interactions

    Watanabe T, Iwasaki Y, Morita A, and Kobata K( Role: Joint author ,  Food components activating capsaicin receptor TRPV1.)

    Wiley-Blackwell  2009.01  ( ISBN:9780813800332

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    Language:English   Book type:Scholarly book

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Misc 【 display / non-display

  • Laboratory internship program for high school students.

    Masanori Katakura, Kenji Kobata

    Journal of Josai Community Liaison Center   ( 3 )   57 - 64   2023.03

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    Authorship:Last author   Language:Japanese   Publishing type:Rapid communication, short report, research note, etc. (bulletin of university, research institution)  

  • カプシノイド Invited

    古旗賢二

    Functional Food   14 ( 3 )   182 - 187   2020.09

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)  

  • 城西大学薬学部における専門職連携教育–彩の国連携力育成プロジェクト– Reviewed

    古屋牧子,細谷 治,上田秀雄,大嶋 繁,古旗賢二,高尾浩一,掘 由美子,小林大介,田口孝行,新井利民,柴崎智美,勝木裕仁,白幡 晶

    城西大学教職課程センター紀要   91 - 96   2019.03

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    Language:Japanese   Publishing type:Rapid communication, short report, research note, etc. (bulletin of university, research institution)  

  • The biological efficacy of natural products against acute and chronic inflammatory diseases in the oral region Invited Reviewed International journal

    Toshiaki Ara, Sachie Nakatani, Kenji Kobata, Norio Sogawa, Chiharu Sogawa

    Medicines   5 ( 4 )   122   2018.12

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    Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:MDPI  

  • Effects of food composition on the differentiation response of bone marrow-derived somatic cells

    14   14 - 18   2018.10

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    Authorship:Lead author   Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

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Presentations 【 display / non-display

  • カプシノイド等の健康機能性について Invited

    古旗賢二

    令和2年特産農産物セミナー  2021.01 

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    Event date: 2021.01

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:オンライン  

  • エラグ酸の腸内代謝物であるウロリチン類の有用性 Invited

    古旗賢二

    ダイセルリバネス講演会「食と腸内環境から人の健康を考える」  2021.01 

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    Event date: 2021.01

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:オンライン  

  • カプシエイト発見から20年:発見から機能性食品応用までと今後への期待 Invited

    古旗賢二

    第73回日本栄養・食糧学会大会関連学術集会 栄養学若手研究者の集い  2019.05 

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    Event date: 2019.05

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:静岡市(静岡県立大学)  

  • カプシエイト開発に関して Invited

    古旗賢二

    第19回東京ゆりの木会総会講演  2014.07 

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    Event date: 2014.07

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:東京都千代田区  

  • 肥満と健康食品 Invited

    古旗賢二

    第51回城西大学薬学部生涯教育講座  2014.05 

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    Event date: 2014.05

    Language:Japanese   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

    Venue:埼玉県坂戸市  

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Industrial Property Rights 【 display / non-display

  • 破骨細胞分化抑制剤

    長田光正,山下和彦,成廣和枝,中澤輝之,和田政裕,古旗賢二

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    Application no:2021-164406  Date applied:2022

  • 閉経後の女性の筋肉の重量を増加させるための組成物

    中島賢則,古旗賢二,中谷祥恵

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    Application no:2021-93239(P2021-93239)  Date applied:2021.06

    Announcement no:2022-185501(P2022-185501A)  Date announced:2022.12

    Country of applicant:Domestic   Country of acquisition:Domestic

  • 間葉系幹細胞に対する増殖促進剤

    長田光正,山下和彦,成廣和枝,中澤輝之,和田政裕,古旗賢二,中谷祥恵

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    Application no:2021-164407  Date applied:2021

  • OSTEOCLAST DIFFERENTIATION INHIBITOR CONTAINING UROLITHIN

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    Application no:WO2019163437  Date applied:2019

    Country of applicant:Domestic   Country of acquisition:Domestic

  • ウロリチン類を含有する前駆脂肪細胞分化抑制剤

    古旗賢二,中谷祥恵,工藤眞丈

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    Application no:P2016-177083  Date applied:2016.09

    Announcement no:P2018-39769A  Date announced:2018.03

    Country of applicant:Domestic   Country of acquisition:Domestic

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Awards 【 display / non-display

  • 日本農芸化学会中部支部会維持会員賞

    2006   日本農芸化学会中部支部   LC/MS/MSを用いたトウガラシ辛味関連化合物の生合成経路の解明

    菅原 舞,三村真琴,古旗賢二,矢澤 進,渡辺達夫

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    Award type:Award from Japanese society, conference, symposium, etc.  Country:Japan

  • 日本農芸化学会 B.B.B論文賞

    2002   日本農芸化学会   Enzymatic Synthesis of a Capsinoid by the Acylation of Vanillyl Alcohol with. Fatty Acid Derivatives Catalyzed by Lipases

    古旗賢二,川口真波,渡辺達夫

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    Award type:Honored in official journal of a scientific society, scientific journal  Country:Japan

  • 信州農林科学振興会賞

    1998   信州農林科学振興会   無辛味トウガラシ成分,カプシエイト類の酵素的合成法の確立

    古旗賢二

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    Award type:Award from publisher, newspaper, foundation, etc.  Country:Japan

Scientific Research Funds Acquisition Results 【 display / non-display

  • トウガラシにおけるカプサイシン生合成の種・組織特異性の打破と成分育種展開

    Grant number:21H02187  2021.04 - 2025.03

    基盤研究(B) 

    田中義行、大野 翔、杉山立志、古旗賢二、佐野香織

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    Authorship:Coinvestigator(s) 

  • 長鎖アシル基を持つ無辛味カプサイシン類縁体の唐辛子食品からの探索と生成機構の解明

    2009.04 - 2012.03

    科学研究費補助金  基盤研究(C)

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    長鎖アシル基を持つ無辛味カプサイシン類縁体の唐辛子食品からの探索と生成機構の解明

  • 新規トウガラシ成分カプシエイトの生合成経路の解明と辛味発現に関与する因子の探索

    2007.04 - 2009.03

    科学研究費補助金  基盤研究(C)

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    新規トウガラシ成分カプシエイトの生合成経路の解明と辛味発現に関与する因子の探索

  • カプシノイドのアドレナリン分泌活性による体熱産生効果の評価と,酵素的合成法の確立

    2000.04 - 2002.03

    科学研究費補助金  若手研究(B)

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    シノイドのアドレナリン分泌活性による体熱産生効果の評価と,酵素的合成法の確立

Other External Funds 【 display / non-display

  • トウガラシの辛さを自在に操れるか? 〜1アミノ酸の違いがもたらすカプサイシン生合成効率の違い〜

    2021.04 - 2023.03

    城西大学  学長所管研究奨励金 

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    Authorship:coinvestigator  Grant type:Competitive

    Grant amount:\1300000

  • 高大連携に向けた高校生研究室インターンシップの実施

    2021.04 - 2023.03

    城西大学  学長所管研究奨励金 

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    Authorship:coinvestigator  Grant type:Competitive

    Grant amount:\700000

  • 薬科学研究を基盤としたハラール研究の実質化と体系化

    2017.04 - 2019.03

    城西大学  学長所管研究奨励金 

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    Authorship:principal_investigator  Grant type:Competitive

  • 耕作放棄地活用を通じた問題解決型教育プログラムの開発・研究

    2010.04 - 2012.03

    城西大学  学長所管研究奨励金 

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    Authorship:coinvestigator  Grant type:Competitive

Past of Commissioned Research 【 display / non-display

  • 新品種の弱辛味トウガラシの機能性表示届に関する可能性の検討

    2021.11 - 2022.03

    合同会社わざあり  委託研究(わざあり)  General Consignment Study 

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    Authorship:Principal investigator 

    Grant amount:\550000 ( Direct Cost: \550000 )