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Affiliation |
Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences |
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Title |
Assistant Professor |
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External Link |
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NOMURA Harue
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Degree 【 display / non-display 】
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博士（薬科学） ( 2015.03 城西大学 )
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修士（生命科学） ( 2007.03 北里大学 )
From School 【 display / non-display 】
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Teikyo University Faculty of Science and Engineering Graduated
- 2005.03
Country：Japan
From Graduate School 【 display / non-display 】
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Kitasato University Master's Course Completed
2005.04 - 2007.03
Country：Japan
Employment Record in Research 【 display / non-display 】
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Josai University Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences Assistant Professor
2018.04
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Josai University Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences Research Assistant
2007.04 - 2018.03
Professional Memberships 【 display / non-display 】
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日本防菌防黴学会
2014.05
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日本細菌学会
2007.12
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日本薬学会
2006.01
Qualification Acquired 【 display / non-display 】
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High School Teacher Specialization License
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First Kind of Junior High School Teacher License
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First Kind of High School Teacher License
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Junior High School Teacher Specialization License
Papers 【 display / non-display 】
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Effects of oakmoss components on extra- and intracellular Legionella pneumophila and its host Acanthamoeba castellanii Reviewed
Harue Nomura, Nobumasa Suda, Yasuyo Kawano, Yasunori Isshiki, Keisuke Sakuda, Katsuya Sakuma, Seiichi Kondo
Biocontrol Science 27 ( 1 ) 21 - 29 2022
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal) Publisher：日本防菌防黴学会
Acanthamoeba castellanii is a ubiquitous organism found in environmental water. The amoeba is pathogenic to toward humans and is also a reservoir of bacteria of the genus Legionella, a causative agent of legionellosis. Oakmoss, a source of natural fragrance ingredients, and its components are antibacterial agents that are specifically active against the genus Legionella. In the present study, oakmoss and its components were investigated for their inhibitory effects on total (extra- and intracellular) Legionella pneumophila within A. castellanii and on L. pneumophila within A. castellanii. Among the oakmoss components, 3-hydroxy-5-methylphenyl 2,4-dihydroxy-6-methylbenzoate (1), 3-methoxy-5-methylphenyl 2,4-dihydroxy-6-methylbenzoate (2), and 8-(2,4-dihydroxy-6-(2-oxoheptyl)phenoxy)-6-hydroxy-3-pentyl-1H-isochromen-1-one (8) reduced the number of total bacteria (extra- and intracellular) in a test culture and also exhibited high amoebicidal activity against L. pneumophila within A. castellanii at concentrations lower than their IC50 values for A. castellanii. In contrast, 6,8-dihydroxy-3-pentyl-1H-isochromen-1-one (5) reduced the total number of L. pneumophila and, also that of total bacteria after 24 h of treatment (P < 0.05), whereas the compound did not exhibit amoebicidal activity against L. pneumophila within A. castellanii at concentrations lower than its IC50 value against A. castellanii. Thus, it is suggested that these oakmoss components could be good candidates for disinfectants to protect from Legionella infection.
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香料のメチシリン耐性黄色ブドウ球菌（MRSA）の抗菌薬感受性増強効果 Reviewed
野村陽恵、石崎美香、喜多村幸、一色恭徳、作田圭亮、佐久間克也、近藤誠一
22 ( 3 ) 2021
Authorship：Lead author Language：Japanese Publishing type：Research paper (scientific journal) Publisher：AROMA RESEARCH
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天然香料とその主要含有成分のメチシリン耐性黄色ブドウ球菌（MRSA）の抗菌薬感受性増強効果 Reviewed
野村陽恵、若島果穂、一色恭徳、作田圭亮、佐久間克也、近藤誠一
AROMA RESEARCH 22 ( 3 ) 162 - 168 2021
Authorship：Lead author Language：Japanese Publishing type：Research paper (scientific journal)
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Evaluation of Antibacterial Activity Expression of the Hinokitiol/Cyclodextrin Complex Against Bacteria Reviewed International journal
Yutaka Inoue, Rina Suzuki, Isamu Murata, Harue Nomura, Yasunori Isshiki, Ikuo Kanamoto
ACS OMEGA 5 ( 24 ) 27180 - 27187 2020
Language：English Publishing type：Research paper (scientific journal)
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Preparation, Characterization, and Study of the Antimicrobial Activity of a Hinokitiol-Copper(II)/<gamma>-Cyclodextrin Ternary Complex Reviewed
Rina Suzuki, Yutaka Inoue, Isamu Murata, Harue Nomura, Yasunori Isshiki, Masashi Hashimoto, Yasuhiro Kudo, Hiroaki Kitagishi, Seiichi Kondo, Ikuo Kanamoto
Journal of Molecular Structure 1194 19 - 27 2019
Language：English Publishing type：Research paper (scientific journal)
Presentations 【 display / non-display 】
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MRSAの抗菌薬感受性に対するCaryophyllene類縁体の影響
野村陽恵、山下雅唯那、板倉明日望、佐久間克也、一色恭徳
日本薬学会第143年会 2023.03 日本薬学会
Event date： 2023.03
Language：Japanese Presentation type：Poster presentation
Venue：札幌
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香料の緑膿菌のバイオフィルム形成に対する影響
芦澤怜奈,野村陽恵,佐久間克也,一色恭徳
日本薬学会第142年会 日本薬学会
Event date： 2022.03
Language：English Presentation type：Poster presentation
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香料と抗菌薬の Legionella pneumophila に対する抗菌作用の解析
小島菜緒,野村陽恵,作田圭亮,佐久間克也,一色恭徳,近藤誠一
第48回日本防菌防黴学会年次大会 日本防菌防黴学会
Event date： 2021.09
Language：Japanese Presentation type：Poster presentation
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香料の緑膿菌薬剤排出ポンプに対する影響
野村陽恵, 一色恭徳, 作田圭亮, 佐久間克也, 近藤誠一
日本薬学会第140年会
Event date： 2020.03
Language：Japanese Presentation type：Poster presentation
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香料のMRSA抗菌薬感受性増強作用の機序解析
森貴世考、森瑞生、野村陽恵、一色恭徳、作田圭亮、佐久間克也、近藤誠一
日本薬学会第140年会
Event date： 2020.03
Language：Japanese Presentation type：Poster presentation