TAKAO Koichi

写真a

Affiliation

Faculty of Pharmaceutical Sciences Department of Pharmaceutical Technochemistry

Title

Professor

External Link
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Degree 【 display / non-display 】

  • Ph.D ( 1999.03   Josai University )

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Research Areas 【 display / non-display 】

  • Life Science / Pharmaceutical analytical chemistry and physicochemistry

  • Life Science / Pharmaceutical hygiene and biochemistry

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From School 【 display / non-display 】

  • Josai University   Faculty of Pharmaceutical Science   Graduated

    - 1994.03

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    Country：Japan

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From Graduate School 【 display / non-display 】

  • Josai University   Graduate School, Division of Pharmaceutical Sciences   Doctor's Course   Completed

    - 1999.03

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    Country：Japan

  • Josai University   Graduate School, Division of Pharmaceutical Sciences   Master's Course   Completed

    - 1996.03

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    Country：Japan

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Studying abroad experiences 【 display / non-display 】

  • 1999.09 - 2001.03   ルンド大学医学部   博士研究員

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Employment Record in Research 【 display / non-display 】

  • Josai University   Faculty of Pharmaceutical Sciences   Department of Pharmaceutical Technochemistry   Professor

    2022.04

  • Josai University   Faculty of Pharmaceutical Sciences   Department of Pharmaceutical Technochemistry   Associate Professor

    2017.04 - 2022.03

  • Josai University   Faculty of Pharmaceutical Sciences   Assistant Professor

    2007.04 - 2017.03

  • Josai University   Faculty of Pharmaceutical Sciences   Research Assistant

    2001.04 - 2007.03

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External Career 【 display / non-display 】

  • ルンド大学医学部   博士研究員

    1999.09 - 2001.03

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    Country：Sweden

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Professional Memberships 【 display / non-display 】

  • 日本ポリアミン学会

    2010.04

  • 日本生化学会

    1996.04

  • 日本薬学会

    1994.04

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Qualification Acquired 【 display / non-display 】

  • Pharmacist

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Research Career 【 display / non-display 】

  • 細胞内アクロレイン追跡法の開発

    Ordinary Research  

    Project Year： 2022.04  -   

  • 天然物をシードとした誘導体合成と生物活性の評価

    Ordinary Research  

    Project Year： 2012.04  -   

  • 蛍光性基質を用いる新規ポリアミン酸化酵素活性測定法の開発

    The Other Research Programs  

    Project Year： 2007  -  2008 

  • 食餌由来ポリアミンの糖尿病病態に与える影響

    Ordinary Research  

    Project Year： 2005.04  -  2012.03 

  • 食餌由来ポリアミンにより変動する遺伝子発現の網羅的解析

    Ordinary Research  

    Project Year： 2004.04  -  2012.03 

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Papers 【 display / non-display 】

  • Caldomycin, a new guanidopolyamine produced by a novel agmatine homocoupling enzyme involved in homospermidine biosynthesis. Reviewed International coauthorship

    Teruyuki Kobayashi, Akihiko Sakamoto, Tamao Hisano, Keiko Kashiwagi, Kazuei Igarashi, Koichi Takao, Takeshi Uemura, Takemitsu Furuchi, Yoshiaki Sugita, Toshiyuki Moriya, Tairo Oshima and Yusuke Terui

    Sci. Rep.   14 ( 1 )   7566   2024.03

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    Language：English   Publishing type：Research paper (scientific journal)  

  • Synthesis of 2,8-Dioxabicyclo[3.3.1]nonane Derivatives and Their Neuroprotective Activities Reviewed

    Hitoshi Kamauch, Akifumi Takanashi, Mitsuaki Suzuki, Kouki Izumi, Koichi Takao, Yoshiaki Sugita

    Chem.Pharm.Bull.   72 ( 1 )   56 - 60   2024.01

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Bulletins of the Pharmaceutical Society of Japan  

  • A Tricyclic Aromatic Polyketide Isolated from the Marine-derived Fungus Curvularia aeria Reviewed

    Hitoshi Kamauchi, Mayu Tanaka, Mitsuaki Suzuki, Miho Furukawa, Atsushi Ikeda, Chihiro Sasho, Yuka Kiba, Masashi Kitamura, Koichi Takao, Yoshiaki Sugita

    Chem.Pharm.Bull.   72 ( 1 )   98 - 101   2024.01

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Bulletins of the Pharmaceutical Society of Japan  

  • Synthesis and biological evaluation of 2-azolylmethylene-3-(2H)-benzofuranone derivatives as potent monoamine oxidases inhibitors Reviewed

    Koichi Takao, Yuka Kubota, Kota Kurosaki, Hitoshi Kamauchi, Yoshihiro Uesawa, Yoshiaki Sugita

    Chem.Pharm.Bull.   72 ( 1 )   109 - 120   2024.01

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    Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：Bulletins of the Pharmaceutical Society of Japan  

  • Intracellular polyamine depletion induces N-linked galactosylation of the monoclonal antibody produced by CHO DP-12 cells. Reviewed

    Rin Miyajima, Hitomi Manaka, Tatsuya Honda, Noritaka Hashii, Masato Suzuki, Masahiro Komeno, Koichi Takao, Akiko Ishii-Watabe, Kazuei Igarashi, Toshihiko Toida, Kyohei Higashi

    J. Biotechnol.   378   1 - 10   2023.11

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    Language：English   Publishing type：Research paper (scientific journal)   Publisher：Bulletins of the Pharmaceutical Society of Japan  

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Books and Other Publications 【 display / non-display 】

  • Methods Mol. Biol. : Protein arginylation

    Koichi Takao（ Role： Sole author ,  Assay of arginyltransferase activity by a fluorescent HPLC method.）

    Human Press  2023 

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    Responsible for pages：129-137   Language：English   Book type：Scholarly book

    DOI： 10.1007/978-1-0716-2942-0_18

  • 保健・医療・福祉のための専門職連携教育プログラムー地域包括ケアを担うためのヒントー

    柴崎智美、米岡裕美、古屋牧子[編著]（ Role： Joint author ,  第3部E）

    ミネルヴァ書房  2019.06  （ ISBN:978-4-623-08553-8 ）

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    Language：Japanese   Book type：Scholarly book

  • Methods Mol. Biol. : Polyamines Methods and Protocols

    Koichi Takao, Yoshiaki Sugita（ Role： Joint author ,  Pentamine as a substrate for measuring spermine oxidase activity）

    Human Press  2018 

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    Language：English   Book type：Scholarly book

  • Methods Mol. Biol. : Protein arginylation

    Koichi Takao（ Role： Sole author ,  Assay of arginyltransferase activity by a fluorescent HPLC method.）

    Human Press  2015 

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    Language：English   Book type：Scholarly book

  • Handbook of Drug-Nutrient Interaction second edition

    （ Role： Joint translator）

    2011.12 

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    Language：Japanese   Book type：Textbook, survey, introduction

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Misc 【 display / non-display 】

  • 【地域教育実践報告】埼玉県における地域住民の質の高い暮らしを目指した専門職連携教育－彩の国連携力育成プロジェクト（SAIPE）

    古屋牧子、上田秀雄、白幡 晶、大嶋 繁、村田　勇、高尾浩一、小糸　寿美、堀 由美子、水野　文夫、岩田　直洋、細谷　治、小林大介

    地域と大学－城西大学・城西短期大学地域連携センター紀要   1   22 - 27   2021

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (bulletin of university, research institution)   Publisher：城西大学・城西短期大学地域連携センター  

  • Development of newly synthesized chromone derivatives with high tumor-specificity against human oral squamous cell carcinoma Reviewed International journal

    Yoshiaki Sugita, Koichi Takao, Yoshihiro Uesawa, Junko Nagai, Yosuke Iijima, Motohiko Sano, Hiroshi Sakagami

    Medicines   2020.08

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    Language：English   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)   Publisher：MDPI  

  • 城西大学薬学部における専門職連携教育ー彩の国連携力育成プロジェクトー Reviewed

    古屋牧子、細谷治、上田秀雄、大島繁、古畑賢二、高尾浩一、他

    城西大学教職課程センター紀要   2019.03

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (bulletin of university, research institution)   Publisher：城西大学教職課程センター  

  • クロモン誘導体の新規抗癌剤としての可能性 Looking back our recent publications of the tumor-specificity of chromone derivatives

    坂上　宏、史　海霞、永井　純子、植沢　芳広、高尾　浩一、杉田　義昭

    New Food Industry   61 ( 1 )   11 - 18   2019.01

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    Language：Japanese   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

  • Recent Progress of Basic Studies of Natural Products and Their Dental Application Reviewed International journal

    Hiroshi Sakagami, TaiheiWatanabe, Tomonori Hoshino, Naoto Suda, Kazumasa Mori, Toshikazu Yasui, Naoki Yamauchi, Harutsugu Kashiwagi, Tsuneaki Gomi, Takaaki Oizumi, Junko Nagai, Yoshihiro Uesawa, Koichi Takao, Yoshiaki Sugita

    Medicines   6 ( 1 )   2018.12

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    Language：English   Publishing type：Article, review, commentary, editorial, etc. (scientific journal)  

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Scientific Research Funds Acquisition Results 【 display / non-display 】

  • MYCNをターゲットとした高リスクタイプ神経芽腫への創薬

    Grant number：24K10939  2024.04 - 2027.03

    科学研究費補助金  基盤研究(C)

    村井 法之

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    Authorship：Coinvestigator(s) 

  • 加齢によるスペルミン分解活性化機構解明と新規抗老化物質の創出

    Grant number：22K11860  2022.04 - 2025.03

    科学研究費補助金  基盤研究(C)

    植村 武史

  • 口腔癌に対する腫瘍選択性磁性体を用いたハイパーサーミアによる低侵襲的治療の開発

    Grant number：20H03893   2020.04 - 2024.03

    科学研究費補助金  基盤研究(B)

    藤内　祝

  • がん細胞に対するクロモン誘導体の選択毒性機構の解明

    Grant number：20K09885   2020.04 - 2023.03

    科学研究費補助金  基盤研究(C)

    坂上　宏

  • 新規3-スチリルクロモン誘導体の口腔癌治療薬としての可能性に関する基礎研究

    Grant number：16K11519  2016.04 - 2019.03

    科学研究費補助金  基盤研究(C)

    坂上　宏

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