Papers - SHIRAHATA Akira
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N1-Nonyl-1,4-diaminobutane ameliorates brain infraction size in photochemically induced thrombosis model mice. Reviewed International journal
Masuko T, Takao K, Samejima K, Shirahata A, Igarashi K, Casero RA Jr, Sugita Y
Neurosci Lett. 672 118 - 122 2018.01
Language：English Publishing type：Research paper (scientific journal)
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Synthesis and evaluation of fatty acid amides on the N-oleoylethanolamide-like activation of peroxisome proliferator activated receptor α Reviewed International journal
Takao K, Noguchi K, Hashimoto Y, Shirahata A, Sugita Y.
Chem Pharm Bull. 63 ( 4 ) 278 - 285 2015.01
Language：English Publishing type：Research paper (scientific journal)
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An example of self-evaluation of a sense of achievement by students in 6-year pharmacy school with the model core curriculum of pharmaceutical education. Reviewed International journal
Shingaki T, Koyanagi J, Nakamura H, Hirata T, Ohta A, Akimoto M, Shirahata A, Mitsumoto A.
Yakugaku Zasshi. 133 ( 1 ) 141 - 148 2013.01
Language：English Publishing type：Research paper (scientific journal)
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Pentamines as substrate for human spermine oxidase. Reviewed International journal
Takao K, Shirahata A, Samejima K, Casero RA, Igarashi K, Sugita Y.
Chem Biol Bull. 36 ( 3 ) 407 - 411 2013.01
Language：English Publishing type：Research paper (scientific journal)
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Polyamine metabolism is involved in adipogenesis of 3T3-L1 cells. Reviewed International journal
Ishii I, Ikeguchi Y, Mano H, Wada M, Pegg AE, Shirahata A
Amino Acids. 42 ( 2-3 ) 619 - 626 2012.01
Language：English Publishing type：Research paper (scientific journal)
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Determination of cellular aminopropyltransferase activity using precolumn fluorescent etheno-derivatization with high-performance liquidchromatography. Reviewed International journal
Yamazaki K, Ikeguchi Y, Niwa T, Hayashi K, Iwaki T, Ishii I, Niitsu M, Pegg AE, Shirahata A.
Anal Sci. 28 ( 6 ) 621 - 624 2012.01
Language：English Publishing type：Research paper (scientific journal)
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A potential estrogen mimetic effect of a bis(ethyl)polyamine analogue on estrogen receptor positive MCF-7 breast cancer cells. Reviewed International journal
Nayvelt I, John S, Hsu HC, Yang P, Liu W, Das G, Hyvönen MT, Alhonen L, Keinänen TA, Shirahata A, Patel R, Thomas T, Thomas TJ.
Amino Acids. 42 ( 2-3 ) 899 - 911 2012.01
Language：English Publishing type：Research paper (scientific journal)
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Enhancement of gastrointestinal absorption of ovalbumin caused by spermine induces an increase in plasma histamine levels in mice sensitized to ovalbumin. Reviewed International journal
Sugita Y, Takao K, Sugino Y, Kuwabara R, Shirahata A.
Biol Pharm Bull. 34 ( 3 ) 415 - 419 2011.01
Language：English Publishing type：Research paper (scientific journal)
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Fluorescent substrates for polyamine catabolic enzymes and transport. Reviewed International journal
Takao K, Shirahata A.
Methods Mol Biol. 720 463 - 474 2011.01
Language：English Publishing type：Research paper (scientific journal)
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Evaluation method for polyamine uptake by N(1)-dansylspermine. Reviewed International journal
Takao K, Sugita Y, Shirahata A.
Amino Acids. 38 ( 2 ) 533 - 539 2010.01
Language：English Publishing type：Research paper (scientific journal)
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Identification of the primary structure and post-translational modification of rat S-adenosylmethionine decarboxylase. Reviewed International journal
Wada M, Shirahata A.
Biol Pharm Bull. 33 ( 5 ) 891 - 894 2010.01
Language：English Publishing type：Research paper (scientific journal)
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Conformational stabilization of rat s-adenosylmethionine decarboxylase by putrescine. Reviewed International journal
Wada M, Shirahata A.
Biol Pharm Bull. 33 ( 11 ) 1800 - 1805 2010.01
Language：English Publishing type：Research paper (scientific journal)
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Assay of N1-acetylpolyamine oxidase activity with N1,N11-didansylnorspermine as the substrate by ion-pair reversed phase high performance liquid chromatography. Reviewed International journal
Takao K, Sugita Y, Shirahata A.
Biol Pharm Bull. 33 ( 7 ) 1089 - 1094 2010.01
Language：English Publishing type：Research paper (scientific journal)
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A conceptual model of the polyamine binding site of N1-acetylpolyamine oxidase developed from a study of polyamine derivatives. Reviewed International journal
Takao K, Shibata S, Ozawa T, Wada M, Sugitia Y, Samejima K, Shirahata A.
Amino Acids. 37 ( 2 ) 401 - 405 2009.01
Language：English Publishing type：Research paper (scientific journal)
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DNA interaction with antitumor polyamine analogues: a comparison with biogenic polyamines Reviewed
N'soukpoé-Kossi CN, Ouameur AA, Thomas T, Shirahata A, Thomas TJ, Tajmir-Riahi HA
Biomacromolecules 9 ( 10 ) 2712 - 2718 2008.10
Language：English Publishing type：Research paper (scientific journal)
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A conceptual model of the polyamine binding site of N (1)-acetylpolyamine oxidase developed from a study of polyamine derivatives. Reviewed
Takao K, Shibata S, Ozawa T, Wada M, Sugitia Y, Samejima K, Shirahata A.
Amino Acids 2008.08
Language：English Publishing type：Research paper (scientific journal)
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Measurement of spermidine/spermine-N1-acetyltransferase activity by HPLC with N1-dansylnorspermine as the substrate Reviewed
Takao, K., Miyatake, S., Fukazawa, K., Wada, M., Sugita, Y. and Shirahata, A.
Anal. Biochem. 376 ( 2 ) 277 - 279 2008.05
Language：English Publishing type：Research paper (scientific journal)
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Attractive forces between cation condensed DNA double helices Reviewed
Todd BA, Parsegian VA, Shirahata A,Thomas TJ, Rau DC
Biophys J. 94 ( 12 ) 4775 - 4782 2008.03
Language：English Publishing type：Research paper (scientific journal)
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Measurement of spermidine/spermine-N1-acetyltransferase activity by high-performance liquid chromatography with N1-dansylnorspermine as the substrate. Reviewed International journal
Takao K, Miyatake S, Fukazawa K, Wada M, Sugita Y, Shirahata A.
Anal Biochem. 376 ( 2 ) 277 - 279 2008.01
Language：English Publishing type：Research paper (scientific journal)
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Formation of spermidine or norspermidine from synthetic diacetylpolyamines by acetylpolyamine oxidase in cultured cells Invited
Takao, K., Ozawa, T., Shibata, S., Wada M., Sugita, Y., Shirahata, A. and Samejima, K
Biol. Pharm. Bull. 30 2389 - 2393 2007.12
Language：English Publishing type：Research paper (scientific journal)
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・ Amine modification of digested peptide at C-terminal end during protein digestion by protease Reviewed
Ito, T., Sugita, Y., Takao, K., Ikeguchi, Y. and Shirahata, A
Biol. Pharm. Bull. 30 ( 10 ) 1838 - 1843 2007.10
Language：English Publishing type：Research paper (scientific journal)
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・ Enhancement of intestinal absorption of macromolecules by spermine in rats Reviewed
Sugita, Y., Takao, K., Toyama, Y. and Shirahata, A.
Amino Acids 33 ( 2 ) 253 - 260 2007.08
Language：English Publishing type：Research paper (scientific journal)
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Synergistic apoptosis of MCF-7 breast cancer cells by 2-methoxyestradiol and bis(ethyl)norspermine Reviewed
Nair SK, Verma A, Thomas TJ, Chou TC, Gallo MA, Shirahata A, Thomas T.
Cancer Lett. 8 ( 250 ) 311 - 322 2007.06
Language：English Publishing type：Research paper (scientific journal)
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・ Formation of polyamine-modified peptides during protein digestion Reviewed
Ito, T., Sugita, Y., Ikeguchi, Y. and Shirahata, A
Biochem. Biophys. Res. Comm. 356 ( 1 ) 159 - 162 2007.04
Language：English Publishing type：Research paper (scientific journal)
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Formation of spermidine or norspermidine from synthetic diacetylpolyamines by acetylpolyamine oxidase in cultured cells. Reviewed International journal
Takao K, Ozawa T, Shibata S, Wada M, Sugita Y, Shirahata A, Samejima K.
Biol Pharm Bull. 30 ( 12 ) 2389 - 2393 2007.01
Language：English Publishing type：Research paper (scientific journal)
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Formation of polyamine-modified peptides during protein digestion. Reviewed International journal
Ito T, Sugita Y, Ikeguchi Y, Shirahata A.
Biochem Biophys Res Commun. 356 ( 1 ) 159 - 162 2007.01
Language：English Publishing type：Research paper (scientific journal)
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Amine modification of digested peptide at C-terminal end during protein digestion by protease. Reviewed International journal
Ito T, Sugita Y, Takao K, Ikeguchi Y, Shirahata A.
Biol Pharm Bull. 30 ( 10 ) 1838 - 1843 2007.01
Language：English Publishing type：Research paper (scientific journal)
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・ Bending of the estrogen response element by polyamines and estrogen receptors alpha and beta: a fluorescence resonance energy transfer study Reviewed
Thomas, T. J., Nair, S. K., Shirahata, A., Gallo, M. A., Thomas, T.
Int. J. Biochem. Cell Biol. 38 ( 7 ) 1191 - 1206 2006.06
Language：English Publishing type：Research paper (scientific journal)
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Bending of the estrogen response element by olyamines and estrogen receptors alpha and beta: a fluorescence resonance energy transfer study. Reviewed International journal
Vijayanathan V, Thomas TJ, Nair SK, Shirahata A, Gallo MA, Thomas T.
Int J Biochem Cell Biol. 38 ( 7 ) 1191 - 1206 2006.01
Language：English Publishing type：Research paper (scientific journal)
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・ Independent roles of eIF5A and polyamines In cell proliferation Reviewed
Nishimura, K., Murozumi, K., Shirahata, A., Park, M.H., Kashiwagi, K., and Igarashi, K.
Biochem. J. 385 779 - 785 2005.06
Language：English Publishing type：Research paper (scientific journal)
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・ Control of spermidine and spermine levels in rat tissues by trans-4-methylcyclohexylamine, a spermidine-synthase inhibitor. Reviewed
Kobayashi, M., Watanabe, T., Xu, Y. J., Tatemori, M., Goda, H., Niitsu, M., Shirahata, A., Samejima, K.
Biol. Pharm. Bull. 28 ( 4 ) 569 - 573 2005.04
Language：English Publishing type：Research paper (scientific journal)
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Ionic, Structural, and Temperature Effects on DNA Nanoparticles Formed by Natural and Synthetic Polyamines Reviewed
Vijayanathan, V., Lyall, J.,Thomas, T., Shirahata, A., and Thomas. T.J.
Biomacromolecules 6 ( 2 ) 1097 - 1103 2005.04
Language：English Publishing type：Research paper (scientific journal)
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Antisense recognition of the HER-2 mRNA: Effects of Phosphorothioate Substitution and Polyamines on DNA/RNA, RNA/RNA, and DNA/DNA Duples Stability Reviewed
Venkiteswaran,S., Vijayanathan, V., Shirahata, A., Thomas, T., and Thomas, T.J.
Biochemistry 44 ( 1 ) 303 - 312 2005.01
Language：English Publishing type：Research paper (scientific journal)
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Bis(ethyl)norspermine potentiates the apoptotic activity of the pure antiestrogen ICI 182780 in breast cancer cells. Reviewed
Balabhadrapathruni S, Santhakumaran LM, Thomas TJ, Shirahata A, Gallo MA, Thomas T.
Oncol Rep. 13 ( 1 ) 101 - 108 2005.01
Language：English Publishing type：Research paper (scientific journal)
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Mammalian spermindine synthase – Identification of cystein residues and Investigation of the putrescine binding site
Goda, H., Watanabe, T., Takeda, N., Kobayashi, M., Makiko Wada, M., Hosoda, H., Shirahata, A., and Samejima, K.
Biol. Pharm. Bull 27 ( 9 ) 1327 - 1332 2004.09
Language：English Publishing type：Research paper (scientific journal)
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Structural and functional relationship among diamines in terms of inhibition of cell growth,
Higashi, K., Yoshida, K., Nishimura,K., Momiyama, E., Kashiwagi, K., Matsufuji, S., Shirahata A., and Igarashi K
J. Biochem. 136 533 - 539 2004.06
Language：English Publishing type：Research paper (scientific journal)
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・ Formation of DNA nanoparticles in the presence of novel polyamine analogues: alaser light scattering and atomic force microscopic study Reviewed
Vijayanathan,V., Thomas, T., Antony, T., Shirahata A., and Thomas. T.J.
Nucleic Acids Res. 32 ( 1 ) 127 - 134 2004.01
Language：English Publishing type：Research paper (scientific journal)
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Synthetic decarboxylated S-adenosyl-L-methionine as a substrate for aminopropyl transferases. Reviewed
Dejima H, Kobayashi M, Takasaki H, Takeda N, Shirahata A, Samejima K.
Biol Pharm Bull. 26 1005 - 1008 2003.06
Language：English Publishing type：Research paper (scientific journal)
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Possible correlation between abilities of a variety of polyamines to increase activator protein-1 DNA binding and to inhibit [3H]spermidine transport in nuclear fractions of murine brain.
Inoue K, Kuramoto N, Takano K, Taniura H, Sakata K, Ogita K, Shirahata A, Yoneda Y
Brain Res. 987 126 - 130 2003.06
Language：English Publishing type：Research paper (scientific journal)
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Changes in intracellular cocentrations of polyamines during apoptosis of HL-60 cells
Nakamura C, Yasumoto E, Nakano K, Nakayachi T, Hashimoto K, Kusama
Anticancer Res. 23 4797 - 4804 2003.06
Language：English Publishing type：Research paper (scientific journal)
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Self-assembly of an oligodeoxyribonucleotide harboring the estrogen resonce element In the presence of polyamines: Ionic, structural, ans DNA sequence specificity effects
Joan S. Lewis, T.J. Thomas, Akira Shirahata, Thresia Thomas
Biomacromolecules 1 339 - 349 2000.01
Language：English Publishing type：Research paper (scientific journal)
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Changes in intracellular concentrations of amino acids and polyamines during the apoptosis of HL -60 cells
Hiroshi Sakagami, Ei-ichi Fujiwara, Yoshiko Yokote, Kiso Akahane, Kazuhito Asano, Mutsuyuki Kochi, Ei-ichi Hara, Akira Shirahata
Anticancer Res. 20 265 - 270 2000.01
Language：English Publishing type：Research paper (scientific journal)
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Covalent linkage of polyamines to peptidoglycan in Anaerovibrio Lipolytica
Takashi Hirao, Masahide Sato, Akira Shirahata, Yoshikore Kamio
J. Bacteriol. 182 1154 - 1157 2000.01
Language：English Publishing type：Research paper (scientific journal)
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Identification of the putrescine recognition site on polyamine transport ptotein PotE
Keiko Kashiwagi, Akiko Kuraishi, Hideyuki Tomitori, Atsuko Igarashi, Kazuhiro Nishimura, Akira Shirahata, Kazuei Igarashi
J. Biol. Chem. 275 36007 - 36012 2000.01
Language：English Publishing type：Research paper (scientific journal)
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Measurement of macromolecule-bound and ultra-filtrable polyamines In rat liver homogenized without buffer
Yong Ji Xu, Naomi Furuumi, Keijiro Samejima, Masaru Niitsu, Akira Shirahata
Biol. Pharm. Bull. 23 1021 - 1026 2000.01
Language：English Publishing type：Research paper (scientific journal)
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Molecular orrelates of the action of bis(ethyl)polyamines In breast cancer cell growth Inhibition and apoptosis
Carol A. Faaland, T.J. Thomas, Srivani Balabhadrapathruni, Theirry Langer, Somia Mian, Akira Shirahata, Michael A. Gallo, Thresia Thomas
Biochem. Cell Bil. 78 415 - 426 2000.01
Language：English Publishing type：Research paper (scientific journal)
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Primary structure of rat spermidine synthase: An example of refining the cDNA-derived amino acid sequence
Makiko Wada, Daisuke Amano, Harumi Hosoda, Akira Shirahata, Keijiro Samejima, Anthony E. Pegg
Biol. Pharm. Bull. 22 889 - 895 1999.01
Language：English Publishing type：Research paper (scientific journal)
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Ionic and Structural Specificity Effects of Natural and Synthetic Polyamines on the Aggregation and Resolubilization of Single-, Double-, and Triple-Stranded DNA
Muthesamy Saminathan, Thomas Antony, Akira Shirahata, Leonard H. Sigal, Thresia Thomas, T.J. Thomas
Biochemistry 38 3821 - 3830 1999.01
Language：English Publishing type：Research paper (scientific journal)
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Selectivity of Polyamines on the Stability of RNA-DNA Hybrids Containing Phosphodiester and Phosphorothioate Oligodeoxyribonucleotides
Thomas Antony, Thresia Thomas, Akira Shirahata, T.J. Thomas
Biochemistry 38 10775 - 10784 1999.01
Language：English Publishing type：Research paper (scientific journal)
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Facilitation of the Cellular Uptake of a Triplex-Forming Oligonucleotide by Novel Polyamine Analogues: Structure-Activity Relationships
R.M. Thomas, Thresia Thomas, Makiko Wada, Leonard H. Sigal, Akira Shirahata, T.J. Thomas
Biochemistry 38 13328 - 13337 1999.01
Language：English Publishing type：Research paper (scientific journal)
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Activation of nuclear factor by polyamies in breast cancer cells
Neha. Shah, Thresia Thomas, Akira Shirahata, Leonard H. Sigal, T.J. Thomas
Biochemistry 38 14763 - 14774 1999.01
Language：English Publishing type：Research paper (scientific journal)
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Antitumor Effects of bis(ethyl)polyamine analogs on mammary tumor debelopment in FVB/NTgN(MMTVnew) transgenic mice
Muthusamy Saminathan, Neha Shah, Thomas Antony, Salim Haddad, Peter Amenta, Akira Shirahata, T.J. Thomas, Thresua Thomas
Cancer Lett. 146 15 - 23 1999.01
Language：English Publishing type：Research paper (scientific journal)
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Selectivity of Spermine Homolos on Triplex DNA Stabilization
Thomas Antony, Thresia Thomas, Akira Shirahata, Leonard H. Sigal, T.J. Thomas
Antisence and Nucleic Acid Drug Development 9 221 - 231 1999.01
Language：English Publishing type：Research paper (scientific journal)
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Preparation and Usefulness of Some Fluorogenic Substrate for Assay of Arginyl-tRNA-Protein Transferase by HPLC
Koichi. Takao, Y.J. Xu, Keijiro Samejima, Akira Shirahata, Masaru Niitsu
Anal. Biochem. 267 373 - 381 1999.01
Language：English Publishing type：Research paper (scientific journal)
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Increase in Hepatic Content of Oleic Acid Induced by Dehydroepiandrosterone in the Rat
Koichi Imai, Matajirou Koyama, Naomi Kudo, Akira Shirahata, Yoichi Kawashima
Biochem. Pharmacol. 58 925 - 933 1999.01
Language：English Publishing type：Research paper (scientific journal)
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Structure and activity of mouse S-adenosylmethionine decarboxylase gene promotors and properties of the encoded proteins
Kazuhiro Nishimura, Marja Liisananntti, Yasuhide Muta, Keiko Kashiwagi, Akira Shirahata, Marja Janne, Katja Kankare, Olli Janne, Kazuei Igarashi
Biochem. J. 332 651 - 659 1998.01
Language：English Publishing type：Research paper (scientific journal)
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Studies on Inhibition of enzymatic arginyltransfer reaction
Koichi Takao, Toshihisa Igarashi, Hironao Ogiso, Kazuya Ugata, Akira Shirahata, Keijiro Samejima
Chem. Pharm. Bull. 46 1169 - 1172 1998.01
Language：English Publishing type：Research paper (scientific journal)
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Ionspray ionization-mass spectrometric separation and determination of heptafluorobutyryl derivatives of polyamines
Naomi Furuumi, Daisuke Amano, Y.J. Xu, Keijiro Samejima, Masaru Niitsu, Akira Shirahata
Anal. Biochem. 265 253 - 259 1998.01
Language：English Publishing type：Research paper (scientific journal)
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Effect of chain lenghth modefication and bis(ethyl) substitution of spermine analogs on purine-purine-pyrimidine triplex DNA stabilization, aggregation, and conformational transition
M. Musso, Thresia Thomas, Akira Shirataki, Leonard H. Sigal, Michael W. VanDyke, T.J. Thomas
Biochemistry 36 1441 - 1449 1997.01
Language：English Publishing type：Research paper (scientific journal)
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Benzyl-polyamine; novel, potent N-methyl-D-aspartate receptor antagonist
Kazuei Igarashi, Akira Shirahata, Albert J. Pahk, Keiko Kashiwagi, Keith Williams
J. Pharmacol. Exp. Therp. 283 533 - 540 1997.01
Language：English Publishing type：Research paper (scientific journal)
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Effect of natural and synthetic polyamines on the conformation of an oligodeoxyribonucleotide with the estrogen response elements
Thresia Thomas, Gayathri D. Kulkarni, Michael A. Gallo, Norma Greenfield, Joan S. Lewis, Akira Shirahata, T.J. Thomas
Nucl. Acid Res. 25 2396 - 2402 1997.01
Language：English Publishing type：Research paper (scientific journal)
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Pyrimidine-purine^pyrimidine triplex DNA stabilization in the presence of tetramine and pentamine analogues of spermine
T.J. Thomas, Carolyn Ashley, Thresia Thomas, Akira Shirahata, Leonard H. Sigal, Jeremy S. Lee
Biochem. Cell Biol. 75 207 - 215 1997.01
Language：English Publishing type：Research paper (scientific journal)
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Flurometric determination of 1,2,3,4-tetrahydro 6,7-dihydroxy-isoquinoline in biological materials by HPLC
Akira Shirahata, Masanori Yoshioka, Zenzo Tamura
Chem. Pham. Bull. 45 1814 - 1819 1997.01
Language：English Publishing type：Research paper (scientific journal)
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Determination of covalently bound hypusine and deoxyhypusine to protein using submilligram of protein samples
Takanobu Beppu, Akira Shirahata, Keijiro Samejima
Biol. Pharm. Bull. 19 1 - 5 1996.01
Language：English Publishing type：Research paper (scientific journal)
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Structural specificity effects of trivalent analogues on the stabilization and conformational plasticity of triplex DNA
T.J. Thomas, Gayathri D. Kulkarini, Norma J. Greenfield, Akira Shirahata, Thresia Thomas
Biochem. J. 319 591 - 599 1996.01
Language：English Publishing type：Research paper (scientific journal)
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Inhibition of cell growth by combination of a-defluoromethylornithine and an inhibitor of spermine synthase
Yong. He, Tomomi Shimogori, Keiko Kashiwagi, Akira Shirahata, Kazuei Igarashi
J. Biochem. 117 824 - 829 1995.01
Language：English Publishing type：Research paper (scientific journal)
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Inhibition of the growth of various human and mouse tumore cells by 1,15-bis(ethylamino)-4,8,12-triazapentadecane
Kazuei Igarashi, Kunihito Koga, Yong. He, Tomomi Shimogori, H. Ekimoto, Keiko Kashiwagi, Akira Shirahata
Cancer Res. 55 2615 - 2619 1995.01
Language：English Publishing type：Research paper (scientific journal)
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Antagonistic effect of N-(3-aminopropyl)cyclohexylamine on neurotrophic action of spermine in primary cultured rat hippocampal and cellebellar neurons
Peng-jiang, Akira Shirahata, Keijiro Samejima, Hiroshi Saito, Kazuho Abe
Jpn. J. Pharmacol. 69 311 - 315 1995.01
Language：English Publishing type：Research paper (scientific journal)
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Enzymatic aminopropylation of certain secondary amines
Akira Shirahata, H. Hosoda, N. Takanashi, T. Beppu, M. Niitsu, Keijiro Samejima
Biol. Pharm. Bull. 18 355 - 359 1995.01
Language：English Publishing type：Research paper (scientific journal)
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Specific depletion of spermidine and spermine in HTC cells treated with inhibitors of aminopropyltransferase
Takanobu Beppu, Akira Shirahata, Norio Takahashi, Harumi Hosoda, Keijiro Samejima
J. Biochem 117 339 - 345 1995.01
Language：English Publishing type：Research paper (scientific journal)
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Search for novel ligands selective at a polyamine recognition domein on the N-methyl-D-aspartate receptor complex using membrane binding technizues
Yukio Yoneda, Kiyokazu Ogita, Riyo Enomoto, Sumiko Kojima, Makoto Shuto, Akira Shirahata, Keijiro Samejima
Brain Res. 679 15 - 24 1995.01
Language：English Publishing type：Research paper (scientific journal)
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N-(3-Aminopropyl)cyclohexylamine blocks facilitation by spermidine of N-methyl-DL-aspartae-induced seizure in mice in vivo
Peng-jiang Chu, Akira Shirahata, Keijiro Samejima, Hiroshi Saito, Kazuho Abe
Eur. J. Pharmacol. 256 155 - 160 1994.01
Language：English Publishing type：Research paper (scientific journal)
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Correlation between the inhibition of cell gropwth by bis(ethyl)polyamine analogues and the decrease in the function of mitochondria
Yong. He, Toshikazu Suzuki, Keiko Kashiwagi, Kuniko Kusama-eguchi, Akira Shirahata, Kazuei Igarashi
Eur. J. Biochem. 221 391 - 398 1994.01
Language：English Publishing type：Research paper (scientific journal)
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Interaction of a polyamine analogue, 1,19-bis(ethylamino)-5,10,15-triazanonadecane(BE-4-4-4-4), with DNA and effect on growth survival, and polyamine levels in seven human brain tumor cell lines
Hirak S. Basu, Malgorzata Pellarin, Burt G. Fuerstein, Akira Shirahata, Keijiro Samejima, Dennis F. Deen, Laurence J. Marton
Cancre Res. 53 3948 - 3955 1993.01
Language：English Publishing type：Research paper (scientific journal)
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Effects of inhibitors of spermidine synthase and spermine synthase on polyamine synthesis in rat tissues
Akira Shirahata, Norio Takahashi, Takanobu Beppu, Harumi Hosoda, Keijiro Samejima
Biochem. Pharmacol. 45 1897 - 1903 1993.01
Language：English Publishing type：Research paper (scientific journal)
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Overproduction of S-adenosylmethionine decarboxylase in ethylglyoxal bis(guanyl-hydrazone)-resistant mouse FM3A cells
Toshikazu Suzuki, Yasuyo Sadakata, Keiko Kashiwagi, Kenji Hoshino, Yoshimi Kakinuma, Akira Shirahata, Kazuei Igarashi
Eur. J. Biochem. 215 247 - 253 1993.01
Language：English Publishing type：Research paper (scientific journal)
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Correlation between the inhibition of cell growth by accumulated polyamines and the decrease of magnesiun and ATP contents
Yong He, Keiko Kashiwagi, Jun-ichi Fukuchi, Kiyashi Terao, Akira Shirahata, Kazuei Igarashi
Eur. J. Biochem. 217 89 - 96 1993.01
Language：English Publishing type：Research paper (scientific journal)
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Mechanism of the inhibition of cell growth by N1,N12-bis(ethyl)-spermine
Jun-ichi Fukuchi, Keiko Kashiwagi, Kuniko Kusama-eguchi, Kiyashi Terao, Akira Shirahata, Kazuei Igarashi
Eur. J. Biochem. 209 689 - 696 1992.01
Language：English Publishing type：Research paper (scientific journal)
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Polyamine-linked Sepharose: Preparation and Application Mammalian Spermine Synthase
Akira Shirahata, Chang Lie Zhu, Sakae Akatsu, Yasutoshi Suzuki, Keijiro Samejima
Protein Expression and Purification 2 229 - 234 1991.01
Language：English Publishing type：Research paper (scientific journal)
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Puterscine or Spermidine Binding Site of Aminopropyltransferases and Competitive Inhibitors
Akira Shirahata, Toru Morohoshi, Masayo Fukai, Sakae Akatsu, Keijiro Samejima
Biochem. Pharmacol. 41 205 - 212 1991.01
Language：English Publishing type：Research paper (scientific journal)
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Analyses of variously 15N-enriched spermidines during growth of Candida Boidinii cultured with 15N-enriched ammonium sulfate and -15N-enriched L-orniththine
Shinya Otake, Akira Shirahata, Masaru Niitsu, Keijiro Samejima
Chem. Pham. Bull. 38 3172 - 3174 1990.01
Language：English Publishing type：Research paper (scientific journal)
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Inhibitors acting at putrescine or spermidine binding site of aminopropyltransferases
Akira Shirahata, Keijiro Samejima
The Biology and Chemistry of Polyamines(Eds. S.H. Goldemberg and I.D. Algranati) ICSU Press 99 - 102 1990.01
Language：English Publishing type：Research paper (scientific journal)
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Synthesis of spider toxin related compounds
Taiji Asami, Ken'ichi Hagiwara, Hiroyuki Kagechika, Yuichi Hashimoto, Koichi Shudo, Akira Shirahata, Akiko Miwa, Nobufumi Kawai, Terumi Nakajima
Peptide Chemistry 1989(Ed. N. Yanaihara) Protein Research Foundation 233 - 237 1990.01
Language：English Publishing type：Research paper (scientific journal)
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Spermine-like function of N1,N12-Bis(ethyl)Spermine: Stimulation of protein synthesis and cell growth and inhibition of gastric ulceration
Kazuei Igarashi, Keiko Kashiwagi, Jun-ichi Fukuchi, Yashihiko Isobe, Susumu Otomo, Akira Shirahata
Biochem. Biophys. Res. Comm. 172 715 - 720 1990.01
Language：English Publishing type：Research paper (scientific journal)
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Active site of aminopropyltransferases and development of inhibitors
Akira Shirahata, Toru Morohoshi, Masayo Fukai, Sakae Akatsu, Keijiro Samejima
J. Pharmacobio-Dyn. 12 S - 131 1989.01
Language：English Publishing type：Research paper (scientific journal)
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Monospecific antiserumto rat spermidine synthase and its application to rat tissues and several mammals
Akira Shirahata, Toshisuke Takeshima, Keijiro Samejima
J. Biochem 104 717 - 712 1988.01
Language：English Publishing type：Research paper (scientific journal)
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Trans-4-methylcyclohexylamine, a new potent inhibitor of spermidine synthase
Akira Shirahata, Toru Morohoshi, Keijiro Samejima
Chem. Pharm. Bull. 36 3220 - 3222 1988.01
Language：English Publishing type：Research paper (scientific journal)
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Radiommunoassay of L-epinephrine
Yoshioka Masanori, Yoko Kobayashi-Iwase, Kazuo Suga, Akira Shirahata, Zenzo Tamura
Biogenic Amines 4 219 - 227 1987.01
Language：English Publishing type：Research paper (scientific journal)
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Regulation of mammalian S-adenosylmethionine decarboxylase
Anthony E Pegg, Takaaki Kameji, Akira Shirahata, Bruce Stanley, Rentala Madhubala, Antti Pajunen
Adv. Enz. Regul. 27 43 - 55 1987.01
Language：English Publishing type：Research paper (scientific journal)
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Radioimmunoassay of L-norepinephrine
Yoshioka Masanori, Mieko Iwai-Yamazaki, Keiko Kurakazu-Wada, Akira Shirahata, Zenzo Tamura
Biogenic Amines 4 211 - 217 1987.01
Language：English Publishing type：Research paper (scientific journal)
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Increased content of m-RNA for a precursor of S-adenosylmethionine decarboxylase in ratprostate after treatment with 2-defluoromethylornithine
Akira Shirahata, Anthony E. Pegg
J. Biol. Chem. 261 13833 - 13837 1986.01
Language：English Publishing type：Research paper (scientific journal)
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Quantitation of S-adenosylmethionine decarboxylase protein
Akira Shirahata, Kathy L. Christman, Anthoy E. Pegg
Biochemistry 24 4417 - 4423 1985.01
Language：English Publishing type：Research paper (scientific journal)
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Regulation of S-adenosylmethionine decarboxylase activity in rat liver and prostate
Akira Shirahata, Anthony E. Pegg
J. Biol. Chem. 260 9583 - 9588 1985.01
Language：English Publishing type：Research paper (scientific journal)
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Detection of spermine and thermospermine by thin-layer chromatography
Akira Shirahata, Yasuko Takeda, Masako Kawase, Keijiro Samejima
J. Chromatogr 262 451 - 454 1983.01
Language：English Publishing type：Research paper (scientific journal)
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Unexpected conversion of epinephrine into tetrahydroisoquinolines in a solution containing ascorbic acid
Akira Shirahata, Masanori Yoshioka, Zenzo Tamura
Chem. Pharm. Bull. 30 1352 - 1357 1982.01
Language：English Publishing type：Research paper (scientific journal)
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内リンパ嚢外壁転術中における内リンパの採取とその分析
山根 雅昭, 二木 隆, 吉岡 正則, 白幡 晶
耳鼻臨床 75 ( 増5 ) 2290 - 2296 1982.01
Language：English Publishing type：Research paper (scientific journal)
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Studies on radioimmunoassay of metanephrine
Akira Shirahata, Masanori Yoshioka, Misato Matsushita, Zenzo Tamura
Chem. Pharm. Bull. 28 2994 - 3001 1980.01
Language：English Publishing type：Research paper (scientific journal)
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Preparation of specific antibodies to catecholamines and 3,4-dihydroxyphenylalanine. I.Preparation of the conjugates
Akira Miwa, Masanori Yoshioka, Akira Shirahata, Zenzo Tamura
Chem. Pharm. Bull. 25 1904 - 1910 1977.01
Language：English Publishing type：Research paper (scientific journal)
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Preparation of specific antibody to each one of catecholamines and L-DOPA
Akira Miwa, Masanori Yoshida, Akira Shirahata, Yasushi Nakagawa, Zenzo Tamura
Chem. Pharm. Bull. 24 1422 - 1424 1976.01
Language：English Publishing type：Research paper (scientific journal)