Papers - SHIMIZU Jun
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Collagen-derived dipeptide prolyl-hydroxyproline cooperates with Foxg1 to activate the PGC-1α promoter and induce brown adipocytelike phenotype in rosiglitazone-treated C3H10T1/2 cells Reviewed
Kaho Nomura, Yoshifumi Kimira, Ryosuke Kobayashi, Yuna Shiobara, Yoshihiro Osawa, Aya Kataoka-Matsushita, Jun Shimizu, Masahiro Wada and Hiroshi Mano
Frontiers in Nutrition 11 2024.05
Language：English Publishing type：Research paper (scientific journal)
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Promotion and support of lifelong learning for registered dietitians assigned to pharmacies - Collaboration between Pharmacy Registered Dietitian Study Group and Department of Clinical Dietetics and Human Nutrition Invited
2 9 - 14 2022.03
Language：Japanese
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臨床栄養学講座紹介 Invited
清水 純，水野文夫，荒井 健
埼玉県薬剤師会雑誌 50 ( 1 ) 22 - 26 2022.01
Authorship：Lead author Language：Japanese
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Phenotypic and genotypic changes in obesity and type 2 diabetes of male KK mice with aging Reviewed
Iizuka Y, Kim H, Nakasatomi M, Matsumoto A, Shimizu J
Experimental Animals 71 ( 1 ) 71 - 81 2022
Language：English Publishing type：Research paper (scientific journal) Publisher：Japanese Association for Laboratory Animal Science
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Stimulation of the Runx2 P1 promoter by collagen-derived dipeptide prolyl-hydroxyproline bound to Foxg1 and Foxo1 in osteoblasts Reviewed International journal
Nomura K, Kimira Y, Osawa O, Kataoka-Matsushita A, Takao K, Sugita Y, Shimizu J, Wada M, Mano H
Biosci Rep 41 ( 12 ) 2021.11
Language：English Publishing type：Research paper (scientific journal) Publisher：Portland Press
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保険薬局・ドラッグストアに勤務する管理栄養士・栄養士の配置状況と就業の実態 Reviewed
堀由美子，内田博之，清水 純，君羅好史，小口淳美，真野 博
栄養学雑誌 79 ( 4 ) 68 - 77 2021.08
Language：Japanese Publishing type：Research paper (scientific journal) Publisher：日本栄養改善学会
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医療栄養学科 2 年後期科目「総合演習 A」に向けたオンライン対策の取り組み
菊地 秀与，岩田 直洋，内田 博之，清水 純，五十嵐 庸，神内 伸也，伊東 順太，真野 博
城西情報科学研究 28 ( 1 ) 1 - 7 2021.05
Language：Japanese Publishing type：Research paper (bulletin of university, research institution) Publisher：城西大学情報科学研究センター
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管理栄養士資格を有する大学院生による特定健康診査の機会を利用した食育活動
地域と大学 1 ( 1 ) 56 - 57 2021.03
Language：English Publishing type：Research paper (bulletin of university, research institution) Publisher：城西大学
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分子栄養学講座紹介
清水 純，坂本友里
埼玉県薬剤師会雑誌 46 ( 9 ) 22 - 26 2020.09
Authorship：Lead author Language：Japanese
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Protease activity and gel-forming ability of ginger rhizome juice Reviewed International journal
Yamada N, Kokean Y, Umetani K, Shimizu J, Kurita O, Tsumura K.
Journal of Food Research ９ ( ２ ) 30 - 35 2020.02
Language：English Publishing type：Research paper (scientific journal) Publisher： Canadian Center of Science and Education
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Collagen-derived dipeptide prolyl hydroxyproline directly binds to Foxg1 to change its conformation and inhibit the interaction with Runx2. Reviewed International journal
Nomura K, Kimira Y, Osawa Y, Shimizu J, Kataoka-Matsushita A, Mano H
Bioscience, Biotechnology, and Biochemistry 2019.07
Language：English Publishing type：Research paper (scientific journal) Publisher：Taylor & Francis
Other Link： https://www.ncbi.nlm.nih.gov/pubmed/31322484
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The Effects of Collagen Peptide Supplementation on Knee Joint Health. ―A Double—blind, Placebo—controlled, Randomized Trial in Healthy University Students Belonging to a Running Club― Reviewed
Kimira Y, Saito M, Kushibe S, Nomura K, Osawa Y, Sekiguchi Y, Shimizu J, Nakatani S, Koizumi S, Inoue N, Mori Y, Kobayashi J, Mano H.
Japanese Pharmacology Therapeitics 47 ( 9 ) 1455 - 1462 2019.01
Language：English Publishing type：Research paper (scientific journal)
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Collagen-derived dipeptide prolyl-hydroxyproline promotes osteogenic differentiation through Foxg1. Reviewed
Kimira Y, Odaira H, Nomura K, Taniuchi Y, Inoue N, Nakatani S, Shimizu J, Wada M, Mano H.
Cell Mol Biol Lett 22 27 2017.12
Language：English Publishing type：Research paper (scientific journal)
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Mangiferin positively regulates osteoblast differentiation and suppresses osteoclast differentiation. Reviewed
Sekiguchi Y, Mano H, Nakatani S, Shimizu J, Kataoka A, Ogura K, Kimira Y, Ebata M, Wada M
Molecular medicine reports 10 1328 - 1332 2017.06
Language：English Publishing type：Research paper (scientific journal)
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Age-Related Decrease of IF5/BTG4 in Oral and Respiratory Cavities in Mice Reviewed
Mano H, Nakatani S, Kimira Y, Mano M, Sekiguchi Y, Im RH, Shimizu J, Wada M
Bioscience, Biotechnology, and Biochemistry. 79 ( 6 ) 1 - 9 2015.02
Language：English Publishing type：Research paper (scientific journal)
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Oral collagen-derived dipeptides, prolyl-hydroxyproline and hydroxyprolyl-glycine, ameliorate skin barrier dysfunction and alter gene expression profiles in the skin Reviewed
Jun Shimizu, Naoto Asami, Aya Kataoka, Fumihito Sugihara, Naoki Inoue, Yoshifumi Kimira, Masahiro Wada, Hiroshi Mano.
Biochemical and Biophysical Research Communications 456 626 - 630 2015.01
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal) Publisher：Elsevier
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Effect of Dietary Docosahexaenoic Acid Levels on Respiratory Functions in Heart Mitochondria in Rats Reviewed
Yamada N, Shimizu J
American Journal of Nutrition and Food Science 2 ( 2 ) 21 - 25 2015.01
Authorship：Second author Language：English Publishing type：Research paper (scientific journal)
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Citrus limonoid nomilin inhibits osteoclastogenesis in vitro by suppression of NFATc1 and MAPK signaling pathways Reviewed
Kimira Y et al
Phytomedicine 22 1120 - 1124 2015
Language：English Publishing type：Research paper (scientific journal) Publisher：Elsevier
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Collagen-derived dipeptide prolyl-hydroxyproline promotes differentiation of MC3T3-E1 osteoblastic cells. Reviewed
Kimira Y, Ogura K et al
Biochem Biophys Res Commun 453 ( 3 ) 498 - 501 2014.10
Language：English Publishing type：Research paper (scientific journal) Publisher：Elsevier
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デキストラン硫酸ナトリウム誘導大腸炎モデルマウスに与えるセルロース粉末の影響 Reviewed
清水 純，紙谷ひとみ，大竹一男，内田博之，小林 順，真野 博
日本食物繊維学会誌 16 ( 2 ) 71 - 79 2012.12
Authorship：Lead author Language：Japanese Publishing type：Research paper (scientific journal)
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Anti-proliferative effects of Salacia reticulata leaves hot-water extract on interleukin-1β-activated cells derived from the synovium of rheumatoid arthritis model mice Reviewed
Sekiguchi Y et al
BMC Res Notes 5 ( 1 ) 196 2012.04
Language：English Publishing type：Research paper (scientific journal)
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Oral adoministration of N-acetyl glucosamine alters the mRNA expression profile of hyaluronan-related genes in mouse skin. Reviewed
Nakatani S, Mano H, Nakajima H, Shimizu J, Kobata K, Wada M
Chitin and Chitosan Research 18 12 - 24 2012.04
Language：English Publishing type：Research paper (scientific journal) Publisher：日本キチンキトサン学会
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Sri Lankan medicinal plant, “Salacia reticulata.” ameliorated the destruction of skeletal tissues in rheumatoid arthritis in CAIA mice. Reviewed
Yuusuke Sekiguchi, Hiroshi Mano, Sachie Nakatani, Jun Shimizu, and Masahiro Wada
Genes & Nutrition 5 ( 1 ) 89 - 96 2009.06
Language：English Publishing type：Research paper (scientific journal)
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Chondroprotective effectof the bioactive peptide Chondroprotective effectof the bioactive peptidemouse articular cartilage in vitro and in vivo Reviewed
Osteoarthritis and Cartilage 17 ( 12 ) 1620 - 1627 2009.05
Language：English Publishing type：Research paper (scientific journal)
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Mechanisms of blood glucose-lowering effect of aqueous extract from stems of Kothala himbutu (Salacia reticulata) in the mouse. Reviewed
Im R, Mano H, Nakatani S, Shimizu J, Wada M.
Journal of Ethnopharmacology 121 ( 1 ) 234 - 240 2008.12
Language：English Publishing type：Research paper (scientific journal)
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Safety Evaluation of the Aqueous Extract Kothala Himbutu (Salacia reticulata) Stem in the Hepatic Gene Expression Profile of Normal Mice Using DNA Microarrays. Reviewed
Im R, Mano H, Nakatani S, Shimizu J, Wada M
Bioscience, Biotechnology, and Biochemistry 72 ( 12 ) 3075 - 3083 2008.12
Language：English Publishing type：Research paper (scientific journal)
Other Link： http://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-09168451_72_3075
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Aqueous Extract of Kotahla Himbutu (Salacia reticulata) Stems Promotes Oxygen Comsumption and Supresses Body Fat Accumulation in Mice Reviewed
Im R, Mano H, Nakatani S, Shimizu J, Wada M.
Journal of Health Scince 56 ( 6 ) 645 - 653 2008.12
Language：English Publishing type：Research paper (scientific journal)
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DNAマイクロアレイ解析を用いたコメ糠由来スフィンゴ糖脂質画分の食品機能評価 Reviewed
清水 純，小澤真理子，真野 博，岡安重次，和田政裕
日本食品科学工学会誌 54 ( 12 ) 546 - 552 2007.12
Authorship：Lead author Language：Japanese Publishing type：Research paper (scientific journal)
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Glucosamine regulates differentiation of a chondrogenic cell line, ATDC5. Reviewed
Sachie Nakatani, Hiroshi Mano, Ryanghyok IM, Jun Shimizu, Masahiro Wada.
Biological & pharmaceutical bulletin 19 ( 5 ) 433 - 438 2007.05
Language：English Publishing type：Research paper (scientific journal)
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Excess magnesium inhibits excess calcium-induced matrix-mineralization and production of matrix gla protein (MGP) by ATDC5 cells Reviewed
Sachie Nakatani, Hiroshi Mano, Ryanghyok IM, Jun Shimizu, Masahiro Wada.
Biochemical and Biophysical Research Communications 348 ( 3 ) 1157 - 1162 2006.09
Language：English Publishing type：Research paper (scientific journal)
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DNAマイクロアレイ解析を用いた沖縄伝統野菜ニガナ（Crepidiastrum lanceolatum）の食品機能性解析
真野 博，清水 純、他5名
日本栄養・食糧学会誌 59 ( 3 ) 177 - 183 2006.06
Language：Japanese Publishing type：Research paper (scientific journal)
Other Link： http://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-jsnfs.59.177
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グルコサミン塩酸塩およびグルコサミン類似糖が軟骨細胞ATDC5に及ぼす影響 Reviewed
中谷祥恵，真野 博，清水 純，和田政裕
グルコサミン研究 2006.01
Language：Japanese Publishing type：Research paper (scientific journal)
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グルコサミン塩酸塩がマウス硬組織に与える影響 Reviewed
山崎恭枝，中谷祥恵，真野 博，清水 純，和田政裕
グルコサミン研究 2006.01
Language：Japanese Publishing type：Research paper (scientific journal)
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健常女子学生の便通に及ぼすカードラン含有豆腐麺摂取の影響
飯野久和，清水 純，他3名
日本食物繊維学会誌 9 ( 1 ) 2005.06
Language：Japanese Publishing type：Research paper (scientific journal)
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Proportion of Murine Cytotoxic T Cells Is Increased by High-Molecular Weight Fucoidan Extracted from Okinawa Mozuku (Cladosiphon okamuranus)
Jun Shimizu,他5名
Journal of Health Science, 51 (3) 2005.03
Language：English Publishing type：Research paper (scientific journal)
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湿式マイナスイオンサウナの免疫効果 Reviewed
寺沢充夫、上森一樹、宇田川弘幸、小杉和秀、箕輪 功、清水 純、和田政裕、真野 博、鳥越健二
信学技報 104 ( 755 ) 13 - 16 2005.03
Language：Japanese Publishing type：Research paper (scientific journal)
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Jew’s Mellow Leaves (Corchorus olitorius) Suppress Elevation of Postprandial Blood Glucose Levels in Rat and Humans
Satoshi Innami, Jun Shimizu, 他6名
Plant Foods for Human Nutrition, 2005.01
Language：English Publishing type：Research paper (scientific journal)
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Dietary curdlan suppresses dimethylhydrazine-induced aberrant crypt foci formation in Sprague-Dawley rats Reviewed
Jun Shimizu, Keita Kudoh, Masahiro Wada, Toshichika Takita, Satoshi Innami, Akio Maekawa, Tadahiro Tadokoro
Nutrition Research 22 ( 12 ) 867 - 877 2002.12
Language：English Publishing type：Research paper (scientific journal)
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Effect of partially hydrolyzed curdlan on serum and hepatic cholesterol concentrations, and cecal fermentation in rats. Reviewed
Shimizu J, Oka M, Kudoh K, Wada M, Takita T, Innami S, Tadokoro T and Maekawa A.
International Journal for Vitamin and Nutrition Research 72 ( 2 ) 101 - 107 2001.10
Language：English Publishing type：Research paper (scientific journal)
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ラットの消化管機能と脂質代謝に及ぼす大麦フスマ画分の影響 Reviewed
清水 純，玉川浩司，池田彰男，長沼慶太，和田政裕，滝田聖親，印南 敏
日本食物繊維学会誌 5 ( 1 ) 23 - 31 2001.07
Authorship：Lead author Language：Japanese Publishing type：Research paper (scientific journal)
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Dietary curdlan increases proliferation of bifidobacteria in the cecum of rats Reviewed
Jun Shimizu, Noboru Tsuchihashi, Keita Kudoh, Masahiro Wada, Toshichika Takita and Satoshi Innami
Bioscience, Biotechnology, and Biochemistry 65 ( 2 ) 251 - 262 2001.02
Language：English Publishing type：Research paper (scientific journal)
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Dietary docosahexaenoic acid can alter the surface expression of CD4 and CD8 on T cells in peripheral blood Reviewed
Taku Sasaki, Yusuke Kanke, Masahito Nagahashi, Maki Toyokawa, MIchiyo Matsuda, Jun Shimizu, Yoshihisa Misawa,Toshichika Takita
Journal of Agricultural and Food Chemistry 48 ( 4 ) 1047 - 1049 2000.04
Language：English Publishing type：Research paper (scientific journal)
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Dietary n-3 polyunsaturated polyunsaturated fatty acid and status immunocompetent cells involved in innate immunitiy in female rats Reviewed
Taku Sasaki, Yusuke Kanke, Keita Kudoh, Masahito Nagahashi, Maki Toyokawa, Michiyo Matsuda, Jun Shimizu, Toshichika Takita
Annals of Nutrition & Metabolism 41 ( 11 ) 38 - 42 1999.11
Language：English Publishing type：Research paper (scientific journal)
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Curdlan and gellan gum, bacterial gel-forming polysaccharides, exhibit different effects on lipid metabolizm, cecal fermentation and fecal bile acid excretion in rats Reviewed
Journal of Nutritional Science and Vitaminology 45 ( 3 ) 466 - 469 1999.06
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
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Secretion and excretion of immunoglobulin A to cecum and feces differ with type of indigestible saccharides Reviewed
Journal of Nutritional Science and Vitaminology 45 ( 2 ) 173 - 181 1999.04
Authorship：Second author Language：English Publishing type：Research paper (scientific journal)
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Effects of isothiocyanates on growth and metastaticity of B-16-F10 Melanoma cells Reviewed
Taku Sasaki, Keita Kudoh, Yoshio Ozawa, Yasushi Uda, Jun Shimizu, Yusuke Kanke and Toshichika Takita
Nutrition and Cancer 33 ( 1 ) 76 - 81 1999.01
Language：English Publishing type：Research paper (scientific journal)
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Effects of dietary docosahexaenoic acid on surface molecule involved in T cell proliferation Reviewed
Sasaki T et al
Biochim Biophys Acta 1436 519 - 530 1998.12
Language：English Publishing type：Research paper (scientific journal)
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Dried green leaf powders of Jew's mellow (Corchorus),persimmon (Diosphyros kaki) and sweet potato (Ipomoea batatas poir) lower hepatic cholesterol concentration and increase fecal bile acid excretion in rats fed a cholesterol-free diet Reviewed
Innami S et al
Plant Foods for Human Nutrition 52 ( 1 ) 55 - 65 1998.04
Language：English Publishing type：Research paper (scientific journal)
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Effects of dietary n-3-to-n-6 polyunsaturated fatty acid ratio on mammary carcinogenesis in rats Reviewed
Taku Sasaki, Yasuhiko Kobayashi, Jun Shimizu, Masahiro Wada, Satoshi Innnami, Yusuke Kanke
Nutrition and Cancer 30 ( 2 ) 137 - 143 1998.04
Language：English Publishing type：Research paper (scientific journal)
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Changes in platelet aggregation and lipid metabolism in rats given dietary lipids containing different n-3 polyunsaturated Reviewed
Norihiro Yamada, Jun Shimizu, Masahiro Wada, Toshichika Takita and Satoshi Innami
Journal of Nutritional Science and Vitaminology 44 ( 2 ) 279 - 289 1998.04
Authorship：Second author Language：English Publishing type：Research paper (scientific journal)
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Effect of indigestible saccharides on B limphocyte response of intestinal mucosa and cecal fermentation in rats Reviewed
Keita Kudoh, Jun Shimizu, Masahiro Wada,Toshichika Takita, Yusuke Kanke and Satoshi Innami
Journal of Nutritional Science and Vitaminology 44 ( 1 ) 103 - 112 1998.02
Authorship：Second author Language：English Publishing type：Research paper (scientific journal)
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高コレステロール食投与ラットにおける血清，肝臓脂質濃度，糞中ステロイド排泄，並びに消化管機能に及ぼすカードランとジェランガムの影響 Reviewed
清水 純，印南 敏
東農大農学集報 42 ( 1 ) 41 - 47 1997.09
Authorship：Lead author Language：Japanese Publishing type：Research paper (scientific journal)
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Changes in blood coagulation, platelet aggregation, and lipid metabolism in rats given lipids containing docosahexaenoic acid Reviewed
Bioscience, Biotechnology, and Biochemistry 61 ( 9 ) 1454 - 1458 1997.07
Language：English Publishing type：Research paper (scientific journal)
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Effects of different types of dietary fiber preparations isolated from bamboo shoots, edible burdock, aplle and corn on fecal steroid profiles in rats. Reviewed
Journal of Nutritional Science and Vitaminology 42 ( 6 ) 527 - 539 1996.12
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
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Effects of semi-purified dietary fibers isolated from Lagenaria siceraria, Raphanus sativus and Lentinus edodes on fecal steroid Reviewed
Sannoumaru Y et al
Journal of Nutritional Science and Vitaminology 42 ( 2 ) 97 - 110 1996.04
Authorship：Second author Language：English Publishing type：Research paper (scientific journal)