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Affiliation |
Faculty of Pharmaceutical Sciences Department of Pharmaceutical Technochemistry |
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Title |
Professor |
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Laboratory Address |
埼玉県坂戸市けやき台1-1 |
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External Link |
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SUGITA Yoshiaki
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Research Areas 【 display / non-display 】
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Life Science / Pharmaceutical hygiene and biochemistry
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Life Science / Pharmaceutical chemistry and drug development sciences
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Life Science / Food sciences
From School 【 display / non-display 】
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Josai University Faculty of Pharmaceutical Science Graduated
- 1988.03
Country：Japan
From Graduate School 【 display / non-display 】
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Tohoku University Graduate School, Division of Pharmaceutical Sciences Doctor's Course Completed
- 1993.03
Country：Japan
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Josai University Graduate School, Division of Pharmaceutical Sciences Master's Course Completed
- 1990.03
Country：Japan
Employment Record in Research 【 display / non-display 】
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Josai University Professor
2012.04
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Josai University Associate Professor
2010.04 - 2012.03
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Josai University Faculty of Pharmaceutical Sciences Assistant Professor
2007.04 - 2010.03
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Josai University Faculty of Pharmaceutical Sciences Lecturer
2001.04 - 2007.03
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Josai University Faculty of Pharmaceutical Sciences Research Assistant
1993.04 - 2001.03
Professional Memberships 【 display / non-display 】
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日本ポリアミン学会
2010.04
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Japanease Society of Nutrition and Food Science
2001.05
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The Pharmaceutical Society Japan
1988.04
Research Career 【 display / non-display 】
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天然由来化合物の誘導体合成および生物活性の評価
Basic Science Research Program
Project Year： 2012.04 -
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食品成分の腸管機能修飾に伴う免疫応答への影響
Ordinary Research
Project Year： 2006.04 - 2012.04
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食品成分中のポリアミンによる腸管での消化・吸収の修飾
Grant-in-Aid for Scientific Research
Project Year： 2002.04 - 2006.03
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クロモンエノン部の反応性に着目した新規フラボノイド誘導体の合成
Basic Science Research Program
Project Year： 1993.04 - 2002.03
Papers 【 display / non-display 】
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Total synthesis and monoamine oxidase inhibitory activities of (±)-entonalactam A and its derivertives Reviewed
Hitoshi Kamauchi, Momoka Hirata, Koichi Takao, and Yoshiaki Sugita
ACS Omega 7 41804 - 41814 2022.11
Language：English
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Antifungal activity of dehydrocurvularin for Candida spp. through the inhibition of adhesion to human adenocarcinoma cells Reviewed
Hitoshi Kamauchi , Miho Furukawa , Yuka Kiba , Masashi Kitamura , Kanako Usui , Masanori Katakura , Koichi Takao , Yoshiaki Sugita
J. Antibiot. 75 ( 9 ) 530 - 533 2022.07
Language：English
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Polyamines produced by an extreme thermophile are essential for cell growth at high temperature Reviewed
Akihiko Sakamoto, Masatada Tamakoshi, Toshiyuki Moriya, Tairo Oshima, Koichi Takao, Yoshiaki Sugita, Takemitsu Furuchi, Masaru Niitsu, Takeshi Uemura, Kazuei Igarashi, Keiko Kashiwagi, Yusuke Terui
J. Biochem. 172 ( 2 ) 109 - 115 2022.06
Language：English
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A dual anti-inflammatory and anti-proliferative 3-styryl-chromone derivative sensitizes the anti-cancer effects of DNA-damaging agents on colon cancer cells by targeting HMGB1-RAGE-ERK1/2 signaling Reviewed
Sei-ichi Tanuma, Takahiro Oyama, Miwa Okazawa, Hiroaki Yamazaki, Koichi Takao, Yoshiaki Sugita, Sigeru Amano, Takehiko Abe, and Hiroshi Sakagami
Int. J. Mol. Sci. 23 ( 7 ) 3426 2022.03
Language：English
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A benzaldehyde derivative obtained from Hypoxylon truncatum NBRC 32353 treated with hygromycin B Reviewed
Hitoshi Kamauchi, Mitsuaki Suzuki, Koichi Takao, Yoshiaki Sugita
J. Antibiot. 75 ( 1 ) 1 - 8 2022.01
Language：English
Books and Other Publications 【 display / non-display 】
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Methods Mol. Biol.: Polyamines Methods and Protocols
Koichi Takao,Yoshiaki Sugita（ Role： Joint author , Pentamine as a Substrate for Measuring Spermine Oxidase Activity）
Human Press 2018
Language：English Book type：Scholarly book
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食品-医薬品相互作用ハンドブック（共著）
城西大学薬学部医療栄養学科教員（ Role： Joint translator）
丸善株式会社 2005.03 （ ISBN:4-621-07548-9 ）
Language：Japanese
Misc 【 display / non-display 】
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Development of newly synthesized chromone derivatives with high tumor-specificity against human oral squamous cell carcinoma Reviewed
Yoshiaki Sugita, Koichi Takao, Yoshihiro Uesawa, Junko Nagai, Yosuke Iijima, Motohiko Sano, Hiroshi Sakagami
Medicines (MDPI) 7 50 2020.09
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (bulletin of university, research institution)
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Looking back our recent publications of the tumor-specificity of chromone derivatives Reviewed
61 ( 1 ) 11 - 18 2019.01
Language：Japanese Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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Recent progress of basic studies of natural products and their dental application Reviewed
Hiroshi Sakagami, Taihei Watanabe, Tomonori Hoshino, Naoto Suda, Kazumasa Mori, Toshikazu Yasui, Naoki Yamauchi, Harutsugu Kashiwagi, Tsuneaki Gomi, Takaaki Oizumi, Junko Nagai, Yoshihiro Uesawa, Koichi Takao, Yoshiaki Sugita
Medicines 6 ( 1 ) 2018.12
Language：English Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
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Search for new type of anticancer drugs with high tumor specificity and less keratinocyte toxicity Reviewed
Yoshiaki Sugita, Koichi Takao, Yoshihiro Uesawa, Hiroshi Sakagami
Anticancer Res. 37 4459 - 4467 2017.11
Language：English Publishing type：Article, review, commentary, editorial, etc. (scientific journal)
Scientific Research Funds Acquisition Results 【 display / non-display 】
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口腔癌に対する腫瘍選択性磁性体を用いたハイパーサーミアによる低侵襲的治療の開発
Grant number：20H03893 2020.04 - 2024.03
科学研究費補助金 基盤研究(B)
藤内 祝
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がん細胞に対するクロモン誘導体の選択毒性機構の解明
Grant number：20K09885 2020.04 - 2023.03
科学研究費補助金 基盤研究(C)
坂上 宏
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新規３-スチリルクロモン誘導体の口腔癌治療薬としての可能性に関する研究
Grant number：16K11519 2016.04 - 2019.03
科学研究費補助金 基盤研究(C)
坂上 宏
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タンパク質のコンホメーション変化を指標にするプロテオーム解析
Grant number：16590033 2004 - 2006
科学研究費補助金 基盤研究(C)
白幡 晶
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食品成分中のポリアミンによる腸管での消化・吸収の修飾
2003 - 2005
科学研究費補助金 若手研究(B)
杉田 義昭
食品成分の一つとして広範囲かつ多量に存在するポリアミンに着目し、食品成分が薬物、アレルゲンタンパク等の腸管吸収に影響を与える可能性を探る研究の一環として、ポリアミンによる高分子化合物の腸上皮細胞に対する透過の影響を検討する。