Papers - SAKAMOTO Takeshi
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Chronic Administration with FAD012 (3,5-Dimethyl-4-hydroxycinnamic Acid) Maintains Cerebral Blood Flow and Ameliorates Swallowing Dysfunction After Chronic CerebralHpoperfusion in Rats. Reviewed
Takashi Asano, Hirokazu Matsuzaki, Meiyan Xuan, Bo Yuan, Jun Takayama, Takeshi Sakamoto, Mari Okazaki
International Journal of Molecular Sciences 26 ( 7 ) 3277 2025.04
Language：English Publishing type：Research paper (scientific journal)
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分子軌道エネルギーを説明変数とした機械学習による薬効予測 Reviewed
寺前裕之, 三浦優太, 色摩光一, 玄 美燕, 高山 淳, 岡﨑真理, 坂本武史
J. Comput. Chem. Jpn 23 ( 3 ) 80 - 83 2024.10
Authorship：Last author Language：Japanese
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Involvement of the Restoration of Cerebral Blood Flow and Maintenance of eNOS Expression in the Prophylactic Protective Effect of the Novel Ferulic Acid Derivative FAD012 against Ischemia/Reperfusion Injuries in Rats. Reviewed
Takashi Asano, Meiyan Xuan, Naohiro Iwata, Jun Takayama, Kousuke Hayashi, Yosuke Kato, Toshiya Aoyama, Hiroshi Sugo, Hirokazu Matsuzaki, Bo Yuan, Shinya Kamiuchi, Yasuhide Hibino, Takeshi Sakamoto and Mari Okazaki.
Int. J. Mol. Sci. 24 ( 11 ) 9663 2023
Language：English Publishing type：Research paper (scientific journal)
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Prediction of Molecular Properties with Machine Learning and Molecular Orbital Energies. Reviewed
Hiroyuki Teramae, Meiyan Xuan, Jun Takayama, Mari Okazaki, Takeshi Sakamoto
2611 020007-1 - 020007-4 2022.11
Authorship：Last author Language：English Publishing type：Research paper (international conference proceedings)
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Machine Learning Study of Antioxidant Effects with Molecular Orbital Energies as Explanatory Variables Reviewed
Hiroyuki TERAMAE, Meiyan XUAN, Jun TAKAYAMA, Mari OKAZAKI, Takeshi SAKAMOTO
J. Comput. Chem. Jpn. 21 ( 4 ) 103 - 105 2022
Language：Japanese Publishing type：Research paper (scientific journal)
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Enhanced Cytotoxic Effects of Arenite in Combination with Active Bufadienolide Compounds against Human Glioblastoma Cell Line U-87 Reviewed
Bo Yuan, Jingmei Li, Shin-Ich Miyashita, Hidetomo Kikuchi, Meiyan Xuan, Hirokazu Matsuzaki, Naohiro Iwata, Shinya Kamiuchi, Katsuyoshi Sunaga, Takeshi Sakamoto, Yasuhide Hibino and Mari Okazaki
Molecules 27 ( 19 ) 6577 2022
Language：English
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A study of enantioselective syntheses by Sharpless asymmetric oxidation for aryl sulfoxides containing oxygen groups at the ortho position. Reviewed
Takei Takanori, Jun Takayama, Meiyan Xuan, Tomoda Misa, Miyamae Hiroshi, Sakamoto Takeshi
J. Chem. Sci. 133 28 2021
Authorship：Last author Language：English Publishing type：Research paper (scientific journal)
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Possible Prediction of Molecular Properties with Machine Learning and Molecular Orbitak Energies Reviewed
Hiroyuki Teramae, Xuan Meiyan, Tsukasa Yamashita, Jun Takayama, Mari Okazaki, Takeshi Sakamoto
Proceedings of International Symposium on Environmental-Life Science and Nanoscales Technology 2019 (ISENT2019) XVII - XXI 2020.09
Language：English
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Prediction of Molecular Properties by Molecular Orbital Calculations and Machine Learning. Reviewed
Hiroyuki Teramae, Tetsuhide Matsuo, Kazuma Niwatsukino, Ryota Inoue, Shinji Noguchi, Meiyan Xuan, Tsukasa Yamashita, Jun Takayama, Mari Okazaki, Takeshi Sakamoto
J. Comput. Chem. Jpn. 19 ( 2 ) 43 - 45 2020
Authorship：Last author Language：English Publishing type：Research paper (scientific journal)
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Improvement of the solubility and evaluation of the physical properties of an inclusion complex formed by a new ferulic acid derivative and γ-cyclodextrin. Reviewed
Nao Ikeda, Yutaka Inoue, Yuka Ogata, Isamu Murata, Meiyan Xuan, Jun Takayama, Takeshi Sakamoto, Mari Okazaki, IKuo Knamoto
ACS omega 5 12073 - 12080 2020
Language：English Publishing type：Research paper (scientific journal)
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Characterization of 6-bromoferulic acid as a novel commonuse matrix for matrix-assisted laser desorption/ionization timeof-flight mass spectrometry. Reviewed
Yosuke Kato, Narumi Hirosawa, Takeshi Sakamoto, Takeshi Moriguchi, Jun Takayama, Meiyan Xuan, Mari Okazaki, Yuko Suzuki, Ayako Hoshi, Yasushi Sakamoto
Rapid Commun. Mass Spectrom. 34 ( 7 ) 2020
Language：English Publishing type：Research paper (scientific journal)
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Theoretical Study on Antioxidant Properties of Ferulic Acid. Invited
Hiroyuki Teramae, Meiyan Xuan, Tsukasa Yamashita, Jun Takayama, Mari Okazaki, Takeshi Sakamoto
J. Comput. Chem. Jpn. 18 ( 5 ) 211 - 213 2019
Authorship：Last author Language：English Publishing type：Research paper (scientific journal)
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新規シナピン酸誘導体による虚血性脳障害の予防作用：分子メカニズムの解明 Reviewed
廣澤 成美 坂本 安 坂本 武史 岡﨑 真理
埼玉医科大学雑誌 44 ( 2 ) 124 - 126 2018.03
Language：Japanese Publishing type：Research paper (bulletin of university, research institution)
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フェルラ酸のフリーラジカル消去能に関する理論的研究 Reviewed
寺前 裕之, 玄 美燕, 高山 淳, 岡﨑 真理,坂本 武史
J. Comput. Chem. Jpn 17 ( 3 ) 150 - 152 2018
Authorship：Last author Language：Japanese Publishing type：Research paper (scientific journal)
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Protective effects of ferulic acid against chronic cerebral hypoperfusion-induced swallowing dysfunction in rats Reviewed
・ Asano T., Matsuzaki H., Iwata N., Xuan M., Kamiuchi S., Hibino Y., Sakamoto T., Okazaki M.
International Journal of Molecular Sciences 2017
Language：English Publishing type：Research paper (scientific journal)
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Abnomalities in the Metabokisum of Fatty Acids and Triacetylglycerols in the Liver of the Goto-Kakizaki Rat: A Model for Non-Obese Type 2 Diabetes Reviewed
Minako Karahashi, Yuko Hirata-Hanta, Kohei Kawabata, Daisuke Tsutsumi, Misaki Kametani, Nanako Takamatsu, Takeshi Sakamoto, Tohru Yamazaki, Satoshi Asano, Atsushi Mitsumoto, Yoichi Kawashima, Naomi Kudo
Lipid 2016
Language：English Publishing type：Research paper (scientific journal)
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Fatty Acid β-Oxidation Plays a Key Role in Regulating cis-Palmitoleic Acid Levels in the Liver Reviewed
Kohei Kawabata, Minako Karahashi, Takeshi Sakamoto, Yukiho Tsuji, Tohru Yamazaki, Mari Okazaki, Atushi Mitsumoto, Naomi Kudo, Yoichi Kawashima
Biological and Pharmaceutical Bulletin 2016
Language：English Publishing type：Research paper (scientific journal)
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Systematic evaluation of methyl ester bioisosteres in the context of developing alkenyldiarylmethanes (ADAMs) as non-nucleoside reverse transcriptase inhibitors (NNRTIs) for anti-HIV-1 chemotherapy Reviewed
Ayako Hoshi, Takeshi Sakamoto, Jun Takayama, Meiyan Xuan, Mari Okazaki, Tracy Hartman, Robert W. Buckheit, Jr., Christophe Pannecouque, Mark Cushman
Bioorganic & Medicinal Chemistry 2016
Authorship：Corresponding author Language：English Publishing type：Research paper (scientific journal)
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Oxidative De-aromatic Cyclization of N-Substituted Benzanilide Derivatives: Conformational Effect of Amide Groups on the Reaction Reviewed
Kousuke Hayashi, Jun Takayama, Meiyan Xuan, Misaki Suda, Hiroyuki Teramae, Takeshi Sakamoto
Heterocycles 2016
Language：English Publishing type：Research paper (scientific journal)
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Early Release of HMGB1 may Aggravate Neuronal Damage after Trnasient Focal Ischemia in Diabetic Rat Brain Reviewed
Naohiro Iwata, Mri Okazaki, Shinya Kamiuchi, Meiyan Xuan, Hirokazu Matsuzaki, Takeshi Sakamoto, Yasuhide Hibino
International Journal of Diabetes Research 2015
Language：English Publishing type：Research paper (scientific journal)