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Affiliation |
Faculty of Science Department of Mathematics |
SUKEKAWA Tsubasa
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Research Areas 【 display / non-display 】
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Natural Science / Mathematical analysis
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Natural Science / Applied mathematics and statistics
From Graduate School 【 display / non-display 】
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Hokkaido University Graduate School of Science Department of Mathematics Doctor's Course Completed
2020.04 - 2023.03
Country：Japan
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Hokkaido University Graduate School of Science Department of Mathematics Doctor's Course Completed
2018.04 - 2020.03
Country：Japan
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Hokkaido University School of Science Mathematics Doctor's Course Completed
2014.04 - 2018.03
Country：Japan
External Career 【 display / non-display 】
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Department of Mathematics, Josai University Assistant Professor
2026.04
Country：Japan
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Kyoto University Institute for Advanced Study Institute for the Advanced Study of Human Biology Program specific researcher
2023.04 - 2026.03
Country：Japan
Papers 【 display / non-display 】
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S. Seirin-Lee, T. Sukekawa, T. Nakahara, H. Ishii, S.-I. Ei
Journal of Mathematical Biology 80 ( 6 ) 1885 - 1917 2020.03
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal) Publisher：Springer Science and Business Media LLC
Abstract
Cell polarity is an important cellular process that cells use for various cellular functions such as asymmetric division, cell migration, and directionality determination. In asymmetric cell division, a mother cell creates multiple polarities of various proteins simultaneously within her membrane and cytosol to generate two different daughter cells. The formation of multiple polarities in asymmetric cell division has been found to be controlled via the regulatory system by upstream polarity of the membrane to downstream polarity of the cytosol, which is involved in not only polarity establishment but also polarity positioning. However, the mechanism for polarity positioning remains unclear. In this study, we found a general mechanism and mathematical structure for the multiple streams of polarities to determine their relative position via conceptional models based on the biological example of the asymmetric cell division process of C. elegans embryo. Using conceptional modeling and model reductions, we show that the positional relation of polarities is determined by a contrasting role of regulation by upstream polarity proteins on the transition process of diffusion dynamics of downstream proteins. We analytically prove that our findings hold under the general mathematical conditions, suggesting that the mechanism of relative position between upstream and downstream dynamics could be understood without depending on a specific type of bio-chemical reaction, and it could be the universal mechanism in multiple streams of polarity dynamics of the cell.DOI： 10.1007/s00285-020-01484-z
Other Link： http://link.springer.com/article/10.1007/s00285-020-01484-z/fulltext.html
Misc 【 display / non-display 】
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Stability analysis for 2-mode solutions for mass conserved reaction diffusion system Invited
Tsubasa Sukekawa
183 65 - 73 2022.07
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質量保存を伴う線形偏微分方程式の定常解について
祐川 翼
第41回発展方程式若手セミナー報告集 251 - 258 2020.02
Language：Japanese Publishing type：Internal/External technical report, pre-print, etc.
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質量保存をもつ反応拡散系のパルス解の相互作用
祐川翼
第15回数学総合若手研究集会：数学の交叉点-北海道大学数学講究録- 176 615 - 624 2019.03
Presentations 【 display / non-display 】
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Imaging-data based model description tool using optimal transport theory and phase-field method
Tsubasa Sukekawa
JSIAM2025 2025.09
Event date： 2025.09
Language：Japanese Presentation type：Oral presentation (general)
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Imaging data-based model description tool using optimal transport theory and phase-field method
Tsubasa Sukekawa
The Asian Mathematical Conference 2025 2025.08
Event date： 2025.08
Language：English Presentation type：Oral presentation (general)
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Imaging data-based model description tool using optimal transport theory and phase-field method Invited
Tsubasa Sukekawa, Toshiaki Yachimura, Sungrim Seirin-Lee
ACMB-JSMB 2025 2025.07
Event date： 2025.07
Language：English Presentation type：Oral presentation (invited, special)
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保存量をもつ反応拡散コンパートメントモデルにおけるパターンダイナミクスについて Invited
祐川翼
京都大学応用数学セミナー 2025.06
Event date： 2025.06
Language：Japanese Presentation type：Public lecture, seminar, tutorial, course, or other speech
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保存量をもつ反応拡散コンパートメントモデルにおける 線形化固有値問題
祐川 翼
応用数学合同研究集会 2024.12
Event date： 2024.12
Awards 【 display / non-display 】
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The best poster presentation at Joint annual meeting of the Korean Society for Mathematical Biology and the Society for Mathematical Biology 2024
2024.07 KSMB-SMB 2024 SEOUL Imaging Data-based Model Description Tool using Optimal Transport and Phase-field Model
Tsubasa Sukekawa
Teaching Experience 【 display / non-display 】
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Life and Biological Phenomena through Mathematics
2025.04 - 2025.08 Institution：Kyoto University
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応用数学Ⅰ・Ⅱ
2022.04 - 2023.03 Institution：Hokkai-Gakuen University