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Affiliation |
Faculty of Pharmaceutical Sciences Department of Pharmaceutical Technochemistry |
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Laboratory Address |
〒350-0295 埼玉県坂戸市けやき台1-1 |
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Laboratory Phone number |
049-271-8116 |
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Laboratory Fax number |
049-271-8116 |
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External Link |
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KIMURA TORU
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Research Interests 【 display / non-display 】
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上皮膜輸送
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ガン
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多発性嚢胞腎
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傍細胞輸送
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トランスポーター
Research Areas 【 display / non-display 】
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Life Science / Pharmacology / トランスポーター
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Life Science / Cell biology / 上皮膜輸送
From School 【 display / non-display 】
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Toyama Medical and Pharmaceutical University Faculty of Pharmaceutical Science Graduated
1993.04 - 1997.03
From Graduate School 【 display / non-display 】
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Toyama Medical and Pharmaceutical University Graduate School, Division of Pharmaceutical Sciences Doctor's Course Completed
1999.04 - 2002.03
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Toyama Medical and Pharmaceutical University Graduate School, Division of Pharmaceutical Sciences Master's Course Completed
1997.04 - 1999.03
Studying abroad experiences 【 display / non-display 】
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2002.04 - 2006.03 Yale University, department of cellular & molecular physiology post-doctoral associate
Papers 【 display / non-display 】
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Urate Transport via Paracellular Route across Epithelial Cells. Reviewed International journal
Kimura T, Tsukada A, Fukutomi T, Ichida K, Ohtsuki S, Sakurai H
Biol Pharm Bull, 42 ( 1 ) 43 - 49 2019
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
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Paracellular route is the major urate transport pathway across the blood-placental barrier. Reviewed International journal
Uehara I, Kimura T, Tanigaki S, Fukutomi T, Sakai K, Shinohara Y, Ichida K, Iwashita M, Sakurai H
Physiol Rep, 2 2014.05
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
DOI： 10.14814/phy2.12013
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Expression of SLC2A9 isoforms in the kidney and their localization in polarized epithelial cells. Reviewed International journal
Kimura T, Takahashi M, Yan K, Sakurai H
PLoS One 9 ( 1 ) e84996 2014.01
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
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Protein phosphatase 2A interacts with the Na,K-ATPase and modulates its trafficking by inhibition of its association with arrestin. Reviewed
Kimura T, Han W, Pagel P, Nairn AC, Caplan MJ
PLoS One 6 ( 12 ) e29269 2011
Authorship：Lead author Language：English Publishing type：Research paper (scientific journal)
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Arrestins and spinophilin competitively regulate Na+,K+-ATPase trafficking through association with a large cytoplasmic loop of the Na+,K+-ATPase. Reviewed
Kimura T, Allen PB, Nairn AC, Caplan MJ
Mol Biol Cell 18 ( 11 ) 4508 - 1518 2007
Language：English Publishing type：Research paper (scientific journal)
Awards 【 display / non-display 】
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日本消化吸収学会学会賞 （天野学術研究奨励賞）
2011.10
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公益財団法人 痛風財団 優秀論文賞
2010.12
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杏林大学医学部研究奨励賞
2010.11
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第１回 分子腎臓フォーラム研究奨励賞
2010.09
Scientific Research Funds Acquisition Results 【 display / non-display 】
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アミノ酸輸送体を標的とした新規肝嚢胞治療薬の開発
Grant number：22K06867 2022.04 - 2025.03
Authorship：Principal investigator
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Neuromedin Uのアレルギー性鼻炎の病態への関与と画期的な創薬への解析
Grant number：20K09720 2020.04 - 2023.03
Authorship：Coinvestigator(s)
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抗アミノ酸療法を用いた多発性嚢胞腎の治療戦略
Grant number：19K08687 2019.04 - 2022.03
Authorship：Principal investigator
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血中短鎖脂肪酸濃度を決定付ける肝短鎖脂肪酸取込み調節機構の解明
Grant number：16K08555 2016.04 - 2020.03
Authorship：Coinvestigator(s)
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アミノ酸トランスポーター機能調節による癌の制御
Grant number：15K06879 2015.04 - 2018.03
Authorship：Principal investigator
Teaching Experience 【 display / non-display 】
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薬理学
2006.04 - 2023.03 Institution：Kyorin University
Level：Undergraduate (liberal arts)