研究者詳細 - 高山　淳

論文 - 高山　淳

分割表示 36 件中 1 - 20 件目／全件表示 >>

Polyamine metabolism as a regulator of cellular and organismal aging 査読あり

Takeshi Uemura, Jun Takayama, Akihiro Oguro, Yusuke Terui

Amino Acids 58 ( 7 ) 2026年01月

Design and Synthesis of Ferulic Acid Derivatives with Enhanced Antioxidant and Neuroprotective Activities: Discovery of Dual Antioxidant Agent 査読あり

Koichi Shikama, Jun Takayama 2, Meiyan Xuan, Hirokazu Matsuzaki, Bo Yuan, Hiroyuki Teramae, Mari Okazaki, Takeshi Sakamoto

AppliedChem 5 ( 4 ) 37 2025年12月

FAD012, a Ferulic Acid Derivative, Preserves Cerebral Blood Flow and Blood-Brain Barrier Integrity in the Rat Photothrombotic Stroke Model 査読あり

Hiroshi Sugoh, Hirokazu Matsuzaki, Jun Takayama, Naohiro Iwata, Meiyan Xuan, Bo Yuan, Takeshi Sakamoto, Mari Okazaki

Biomedicines 13 ( 10 ) 2403 2025年09月

CUD003, a Novel Curcumin Derivative, Ameliorates LPS-Induced Impairment of Endothelium-Dependent Relaxation and Vascular Inflammation in Mice 査読あり

Hirokazu Matsuzaki, Anna Arai, Meiyan Xuan, Bo Yuan, Jun Takayama, Takeshi Sakamoto, Mari Okazaki

International journal of molecular sciences 26 ( 18 ) 8850 2025年09月

Chronic Administration with FAD012 (3,5-Dimethyl-4-hydroxycinnamic Acid) Maintains Cerebral Blood Flow and Ameliorates Swallowing Dysfunction After Chronic Cerebral Hypoperfusion in Rats 査読あり

Takashi Asano, Hirokazu Matsuzaki, Meiyan Xuan, Bo Yuan, Jun Takayama, Takeshi Sakamoto, Mari Okazaki

International journal of molecular sciences 26 ( 7 ) 3277 2025年04月

Prediction of pharmacological activity by machine learning using molecular orbital energy as an explanatory variable 査読あり

Journal of Computer Chemistry Japan 23 ( 3 ) 80 - 83 2025年01月

記述言語：日本語

Involvement of the Restoration of Cerebral Blood Flow and Maintenance of eNOS Expression in the Prophylactic Protective Effect of the Novel Ferulic Acid Derivative FAD012 against Ischemia/Reperfusion Injuries in Rats 査読あり

Takashi Asano, Meiyan Xuan, Naohiro Iwata, Jun Takayama, Kousuke Hayashi, Yosuke Kato, Toshiya Aoyama, Hiroshi Sugo, Hirokazu Matsuzaki, Bo Yuan, Shinya Kamiuchi, Yasuhide Hibino, Takeshi Sakamoto, Mari Okazaki

International Journal of Molecular Sciences 24 ( 11 ) 9663 2023年06月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： https://doi.org/10.3390/ijms24119663

分子軌道エネルギーを説明変数とした機械学習査読あり

21 ( 4 ) 103 - 105 2023年04月

記述言語：日本語掲載種別：研究論文（学術雑誌）

DOI： https://doi.org/10.2477/jccj.2023-0001

Prediction of molecular properties with machine learning and molecular orbital energies

Hiroyuki Teramae, Xuan Meiyan, Jun Takayama, Mari Okazaki, Takeshi Sakamoto

AIP Conference Proceedings 2611 2611 ( 1 ) 020007 2022年11月

A study of enantioselective syntheses by Sharpless asymmetric oxidation for aryl sulfoxides containing oxygen groups at the ortho position 招待あり

Takei Takanori, Jun Takayama, Meiyan Xuan, Tomoda Misa, Miyamae Hiroshi, Sakamoto Takeshi

Journal of Chemical Sciences 133 ( 28 ) 2021年03月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： https://doi.org/10.1007/s12039-021-01887-5

Prediction of Molecular Properties by Molecular Orbital Calculations and Machine Learning 査読あり

Hiroyuki Teramae, Tetsuhide Matsuo, Kazuma Niwatsukino, Ryota Inoue, Shinji Noguchi, Meiyan Xuan, Tsukasa Yamashita, Jun Takayama, Mari Okazaki, Takeshi Sakamoto

Journal of Computer Chemistry, Japan 19 ( 2 ) 43 - 45 2020年11月

記述言語：日本語掲載種別：研究論文（学術雑誌）

DOI： https://doi.org/10.2477/jccj.2020-0005

Improvement of the solubility and evaluation of the physical properties of an inclusion complex formed by a new ferulic acid derivative and γ-cyclodextrin 査読あり

Nao Ikeda, Yutaka Inoue, Yuka Ogata, Isamu Murata, Meiyan Xuan, Jun Takayama, Takeshi Sakamoto, Mari Okazaki, IKuo Knamoto

ACS Omega 5 ( 21 ) 12073 - 12080 2020年05月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： https://doi.org/10.1021/acsomega.0c00277

Theoretical Study on Antioxidant Properties of Feluric Acid 査読あり

Hiroyuki Teramae, Meiyan Xuan, Tsukasa Yamashita, Jun Takayama, Mari Okazaki, Takeshi Sakamoto

Journal of Computer Chemistry, Japan 18 ( 5 ) 211 - 213 2020年02月

記述言語：日本語掲載種別：研究論文（学術雑誌）

DOI： https://doi.org/10.2477/jccj.2019-0034

Possible Prediction of Molecular Properties with Machine Learning and Molecular Orbitak Energies 査読あり

Hiroyuki Teramae, Xuan Meiyan, Tsukasa Yamashita, Jun Takayama, Mari Okazaki, Takeshi Sakamoto

Proceedings of International Symposium on Environmental-Life Science and Nanoscales Technology 2019 XVII - XXI 2019年12月

記述言語：英語掲載種別：研究論文（国際会議プロシーディングス）

Characterization of 6-bromoferulic acid as a novel common-use matrix for MALDI-TOF-MS 査読あり

Yosuke Kato, Narumi Hirosawa, Takeshi Sakamoto, Takeshi Moriguchi, Jun Takayama, Meiyan Xuan, Mari Okazaki, Yuko Suzuki, Ayako Hoshi,Yasushi Sakamoto

Rapid Communications in Mass Spectrometry 34 ( 7 ) e8636 2019年10月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： https://doi.org/10.1002/rcm.8636

Potent HIV-1 protease inhibitors incorporating squaramide-derived P2 ligands: Design, synthesis, and biological evaluation 査読あり国際共著

Arun K. Ghosh, Jacqueline N. Williams, Satish Kovela, Jun Takayama, Hannah M. Simpson, D. Eric Walters, Shin-ichiro Hattori, Manabu Aoki, Hiroaki Mitsuya

Bioorganic Medicinal Chemistry Letters 29 ( 18 ) 2565 - 2570 2019年09月

記述言語：英語掲載種別：研究論文（学術雑誌）

DOI： 10.1016/j.bmcl.2019.08.006

Design of novel HIV-1 protease inhibitors incorporating isophthalamide- derived P2-P3 ligands: Synthesis, biological evaluation and X-ray structural studies of inhibitor-HIV-1 protease complex 査読あり

Arun K. Ghosh, Margherita Brindisi, Prasanth R. Nyalapatla, Jun Takayama, Jean-Rene Ella-Menye, Sofiya Yashchuk, Johnson Agniswamy, Yuan-Fang Wang, Manabu Aoki, Masayuki Amano, Irene T. Weber, Hiroaki Mitsuya

Bioorganic & Medicinal Chemistry in press 2017年04月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：ScienceDirect

DOI： 10.1016/j.bmc.2017.04.005

A fission yeast cell-based system for multidrug resistant HIV-1 proteases 査読あり

Zsigmond Benko, Dong Liang, Ge Li, Robert T. Elder, Anindya Sarkar, Jun Takayama, Arun K. Ghosh, Richard Y. Zhao

Cell & Bioscience 2017年01月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：BioMed Central

DOI： 10.1186/s13578-016-0131-5

Hamiltonian algorithm and its application to the aromatic oxidative cyclization on N-methoxy-N-prenylbenzamide 招待あり査読あり

Hiroyuki Teramae, Kousuke Hayashi, Jun Takayama, Takeshi Sakamoto

AIP Conference Proceedings 1790 ( 1 ) 2016年12月

記述言語：英語掲載種別：研究論文（国際会議プロシーディングス）