SUGITA Yoshiaki

写真a

Affiliation

Faculty of Pharmaceutical Sciences Department of Pharmaceutical Technochemistry

Title

Professor

Laboratory Address

埼玉県坂戸市けやき台1-1

External Link

Degree 【 display / non-display

  • 博士(薬学) ( 1993.03   東北大学 )

Research Interests 【 display / non-display

  • 生物有機化学

Research Areas 【 display / non-display

  • Life Science / Pharmaceutical hygiene and biochemistry

  • Life Science / Pharmaceutical chemistry and drug development sciences

  • Life Science / Food sciences

From School 【 display / non-display

  • Josai University   Faculty of Pharmaceutical Science   Graduated

    - 1988.03

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    Country:Japan

From Graduate School 【 display / non-display

  • Tohoku University   Graduate School, Division of Pharmaceutical Sciences   Doctor's Course   Completed

    - 1993.03

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    Country:Japan

  • Josai University   Graduate School, Division of Pharmaceutical Sciences   Master's Course   Completed

    - 1990.03

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    Country:Japan

Employment Record in Research 【 display / non-display

  • Josai University   Professor

    2012.04

  • Josai University   Associate Professor

    2010.04 - 2012.03

  • Josai University   Faculty of Pharmaceutical Sciences   Assistant Professor

    2007.04 - 2010.03

  • Josai University   Faculty of Pharmaceutical Sciences   Lecturer

    2001.04 - 2007.03

  • Josai University   Faculty of Pharmaceutical Sciences   Research Assistant

    1993.04 - 2001.03

Professional Memberships 【 display / non-display

  • 日本ポリアミン学会

    2010.04

  • Japanease Society of Nutrition and Food Science

    2001.05

  • The Pharmaceutical Society Japan

    1988.04

Qualification Acquired 【 display / non-display

  • Pharmacist

 

Research Career 【 display / non-display

  • 天然由来化合物の誘導体合成および生物活性の評価

    Basic Science Research Program  

    Project Year: 2012.04  -   

  • 食品成分の腸管機能修飾に伴う免疫応答への影響

    Ordinary Research  

    Project Year: 2006.04  -  2012.04 

  • 食品成分中のポリアミンによる腸管での消化・吸収の修飾

    Grant-in-Aid for Scientific Research  

    Project Year: 2002.04  -  2006.03 

  • クロモンエノン部の反応性に着目した新規フラボノイド誘導体の合成

    Basic Science Research Program  

    Project Year: 1993.04  -  2002.03 

Papers 【 display / non-display

  • Synthesis and biological evaluation of 2-azolylmethylene-3-(2H)-benzofuranone derivatives as potent monoamine oxidases inhibitors Reviewed

    Koichi Takao, Yuka Kubota, Kota Kurosaki, Hitoshi Kamauchi, Yoshihiro Uesawa, Yoshiaki Sugita

    Chem. Pharm. Bull.   72 ( 1 )   109 - 120   2024.01

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    Language:English  

  • Synthesis of 2,8-dioxabicyclo[3.3.1]nonane derivatives and their neuroprotective activities Reviewed

    Hitoshi Kamauchi, Akifumi Takanashi, Mitsuaki Suzuki, Kouki Izumi, Koichi Takao, Yoshiaki Sugita

    Chem. Pharm. Bull.   72 ( 1 )   56 - 60   2024.01

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    Language:English  

  • A tricyclic aromatic polyketide isolated from the marine-derived fungus Curvularia aeria Reviewed

    Hitoshi Kamauchi, Mayu Tanaka, Mitsuaki Suzuki, Miho Furukawa, Atsushi Ikeda, Chihiro Sasho, Yuka Kiba, Masashi Kitamura, Koichi Takao, Yoshiaki Sugita

    Chem. Pharm. Bull.   72 ( 1 )   98 - 101   2024.01

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    Language:English  

  • Potentiation of anticancer activity of G2/M blockers by mild hyperthermia Reviewed

    Yuya Tagawa, Hiroshi Sakagami, Sei-Ichi Tamura, Shigeru Amano, Shin Uota, Kenjiro Bandow, Mineko Tomomura, Yoshihiro Uesawa, Koichi Takao, Yoshiaki Sugita, Nobuharu Yamamoto, Hideki Sakashita, Rina Nakakaji, Toshiyuki Koizumi, Kenji Mitsudo, Iwai Tohnai

    Anticancer Res.   43 ( 8 )   3429 - 3439   2023.08

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    Language:English  

  • A Comparative study of tumor-specificity and neurotoxicity between 3-styrylchromones and anti-cancer drugs Reviewed

    Tomoyuki Abe, Hiroshi Sakagami, Shigeru Amano, Shin Uota, Kenjiro Bandow, Yoshihiro Uesawa, Shiori U, Hiroki Shibata, Yuri Takemura, Yu Kimura, Koichi Takao, Yoshiaki Sugita, Akira Sato, Sei-Ichi Tanuma, Hiroshi Takeshima

    Medicines   10 ( 7 )   43   2023.07

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    Language:English  

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Books and Other Publications 【 display / non-display

  • Methods Mol. Biol.: Polyamines Methods and Protocols

    Koichi Takao,Yoshiaki Sugita( Role: Joint author ,  Pentamine as a Substrate for Measuring Spermine Oxidase Activity)

    Human Press  2018 

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    Language:English   Book type:Scholarly book

  • 食品-医薬品相互作用ハンドブック(共著)

    城西大学薬学部医療栄養学科教員( Role: Joint translator)

    丸善株式会社  2005.03  ( ISBN:4-621-07548-9

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    Language:Japanese  

Misc 【 display / non-display

  • Development of newly synthesized chromone derivatives with high tumor-specificity against human oral squamous cell carcinoma Reviewed

    Yoshiaki Sugita, Koichi Takao, Yoshihiro Uesawa, Junko Nagai, Yosuke Iijima, Motohiko Sano, Hiroshi Sakagami

    Medicines (MDPI)   7   50   2020.09

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (bulletin of university, research institution)  

  • Looking back our recent publications of the tumor-specificity of chromone derivatives Reviewed

    61 ( 1 )   11 - 18   2019.01

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • Recent progress of basic studies of natural products and their dental application Reviewed

    Hiroshi Sakagami, Taihei Watanabe, Tomonori Hoshino, Naoto Suda, Kazumasa Mori, Toshikazu Yasui, Naoki Yamauchi, Harutsugu Kashiwagi, Tsuneaki Gomi, Takaaki Oizumi, Junko Nagai, Yoshihiro Uesawa, Koichi Takao, Yoshiaki Sugita

    Medicines   6 ( 1 )   2018.12

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    Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

  • Search for new type of anticancer drugs with high tumor specificity and less keratinocyte toxicity Reviewed

    Yoshiaki Sugita, Koichi Takao, Yoshihiro Uesawa, Hiroshi Sakagami

    Anticancer Res.   37   4459 - 4467   2017.11

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    Language:English   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)  

Scientific Research Funds Acquisition Results 【 display / non-display

  • 口腔癌に対する腫瘍選択性磁性体を用いたハイパーサーミアによる低侵襲的治療の開発

    Grant number:20H03893  2020.04 - 2024.03

    科学研究費補助金  基盤研究(B)

    藤内 祝

  • がん細胞に対するクロモン誘導体の選択毒性機構の解明

    Grant number:20K09885  2020.04 - 2023.03

    科学研究費補助金  基盤研究(C)

    坂上 宏

  • 新規3-スチリルクロモン誘導体の口腔癌治療薬としての可能性に関する研究

    Grant number:16K11519  2016.04 - 2019.03

    科学研究費補助金  基盤研究(C)

    坂上 宏

  • タンパク質のコンホメーション変化を指標にするプロテオーム解析

    Grant number:16590033  2004 - 2006

    科学研究費補助金  基盤研究(C)

    白幡 晶

  • 食品成分中のポリアミンによる腸管での消化・吸収の修飾

    2003 - 2005

    科学研究費補助金  若手研究(B)

    杉田 義昭

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    食品成分の一つとして広範囲かつ多量に存在するポリアミンに着目し、食品成分が薬物、アレルゲンタンパク等の腸管吸収に影響を与える可能性を探る研究の一環として、ポリアミンによる高分子化合物の腸上皮細胞に対する透過の影響を検討する。