SAKAMOTO Takeshi

写真a

Affiliation

Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences

Title

Vice President

External Link
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Degree 【 display / non-display 】

  • 博士（薬学） ( 1994.03   城西大学 )

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Research Areas 【 display / non-display 】

  • Life Science / Pharmaceutical chemistry and drug development sciences

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From School 【 display / non-display 】

  • Josai University   Faculty of Pharmaceutical Science   Graduated

    1981.04 - 1985.03

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    Country：Japan

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From Graduate School 【 display / non-display 】

  • Josai University   Graduate School, Division of Pharmaceutical Sciences   Master's Course   Unfinished Course

    1985.04 - 1986.03

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    Country：Japan

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Studying abroad experiences 【 display / non-display 】

  • 2005.09 - 2006.08   Purdue University   Visiting Professor

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Employment Record in Research 【 display / non-display 】

  • Josai University   Vice President

    2023.04

  • Josai University   学長補佐

    2021.05 - 2022.03

  • Josai University   Faculty of Pharmaceutical Sciences   Professor

    2012.04

  • Josai University   Faculty of Pharmaceutical Sciences   Associate Professor

    2010.04 - 2012.03

  • Josai University   Faculty of Pharmaceutical Sciences   Assistant Professor

    2006.10 - 2010.03

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Professional Memberships 【 display / non-display 】

  • American Chemical Society

    2006.04

  • 日本薬学会

    1989.04

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Qualification Acquired 【 display / non-display 】

  • Pharmacist

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Research Career 【 display / non-display 】

  • 新規クルクミン誘導体の効率的合成法の確立と生物活性の評価

    Project Year： 2016  -   

  • 新規フェルラ酸誘導体の効率的合成法の確立と生物活性の評価

    Grant-in-Aid for Scientific Research  

    Project Year： 2014.04  -   

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    生物活性を有するフェルラ酸誘導体の分子設計、合成、生物活性の評価

  • 新規フェルラ酸誘導体の合成とMALDI Matrixへの応用

    Project Year： 2014.04  -   

  • 脱芳香化型酸化反応によるスピロシクロヘキサジエノンーラクタム環の合成と応用

    (not selected)  

    Project Year： 2013.04  -   

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    超原子価ヨウ素試薬を用いて種々のアザスピロ環化合物の効率的な合成法の開発と生物活性の検討

  • HIV-1非核酸系逆転写酵素阻害剤アルケニルジアリールメタン類の開発

    (not selected)  

    Project Year： 2006.10  -   

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    非核酸系逆転写酵素阻害剤としてのアルケニルジアリルメタン類の分子設計と阻害活性の検討

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Papers 【 display / non-display 】

  • Involvement of the Restoration of Cerebral Blood Flow and Maintenance of eNOS Expression in the Prophylactic Protective Effect of the Novel Ferulic Acid Derivative FAD012 against Ischemia/Reperfusion Injuries in Rats. Reviewed

    Takashi Asano, Meiyan Xuan, Naohiro Iwata, Jun Takayama, Kousuke Hayashi, Yosuke Kato, Toshiya Aoyama, Hiroshi Sugo, Hirokazu Matsuzaki, Bo Yuan, Shinya Kamiuchi, Yasuhide Hibino, Takeshi Sakamoto and Mari Okazaki.

    Int. J. Mol. Sci.   24 ( 11 )   9663   2023

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    Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.3390/ijms24119663

  • Machine Learning Study of Antioxidant Effects with Molecular Orbital Energies as Explanatory Variables Reviewed

    Hiroyuki TERAMAE, Meiyan XUAN, Jun TAKAYAMA, Mari OKAZAKI, Takeshi SAKAMOTO

    J. Comput. Chem. Jpn.   21 ( 4 )   103 - 105   2022

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    Language：Japanese   Publishing type：Research paper (scientific journal)  

  • Enhanced Cytotoxic Effects of Arenite in Combination with Active Bufadienolide Compounds against Human Glioblastoma Cell Line U-87 Reviewed

    Bo Yuan, Jingmei Li, Shin-Ich Miyashita, Hidetomo Kikuchi, Meiyan Xuan, Hirokazu Matsuzaki, Naohiro Iwata, Shinya Kamiuchi, Katsuyoshi Sunaga, Takeshi Sakamoto, Yasuhide Hibino and Mari Okazaki

    Molecules   27 ( 19 )   6577   2022

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    Language：English  

    DOI： https://doi.org/10.3390/molecules27196577

  • A study of enantioselective syntheses by Sharpless asymmetric oxidation for aryl sulfoxides containing oxygen groups at the ortho position. Reviewed

    Takei Takanori, Jun Takayama, Meiyan Xuan, Tomoda Misa, Miyamae Hiroshi, Sakamoto Takeshi

    J. Chem. Sci.   133   28   2021

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    Authorship：Last author   Language：English   Publishing type：Research paper (scientific journal)  

    DOI： https://doi.org/10.1007/s12039-021-01887-5

  • Possible Prediction of Molecular Properties with Machine Learning and Molecular Orbitak Energies Reviewed

    Hiroyuki Teramae, Xuan Meiyan, Tsukasa Yamashita, Jun Takayama, Mari Okazaki, Takeshi Sakamoto

    Proceedings of International Symposium on Environmental-Life Science and Nanoscales Technology 2019 (ISENT2019)   XVII - XXI   2020.09

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    Language：English  

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Books and Other Publications 【 display / non-display 】

  • 基礎有機化学問題集　第2版

    西出喜代治, 片岡貞, 廣田耕作（ Role： Joint author）

    廣川書店  2017 

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    Language：Japanese   Book type：Scholarly book

  • 化学構造と薬理作用　医薬品を化学的に読む　第2版

    柴崎正勝, 赤池昭紀, 橋田充,　西出喜代治, 佐々木茂貴, 栄田敏之（ Role： Joint author）

    廣川書店  2015 

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    Language：Japanese   Book type：Scholarly book

  • 基礎有機化学問題集

    廣田 耕作, 西出 喜代治, 片岡 貞　他（ Role： Joint author）

    廣川書店  2014 

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    Language：Japanese   Book type：Scholarly book

  • パートナー薬品製造学改訂第2版

    野上靖純, 田口武夫,　長普子　他（ Role： Joint author）

    南江堂  2012 

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    Language：Japanese   Book type：Scholarly book

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Presentations 【 display / non-display 】

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Scientific Research Funds Acquisition Results 【 display / non-display 】

  • フェルラ酸誘導体FAD012は虚血性脳血管障害に対する予防的治療薬となり得るか？

    Grant number：19K07873  2019.04 - 2023.03

    科学研究費補助金  

  • 新規フェルラ酸誘導体FAD012の虚血性脳障害抑制メカニズムに関する基礎的研究

    Grant number：16K09255  2016.04 - 2019.03

    科学研究費補助金  基盤研究(C)

    岡崎　真理

  • 新規フェルラ酸誘導体の脳虚血性嚥下反射障害に対する予防・改善効果に関する基礎研究

    Grant number：25460910  2013.04 - 2016.03

    科学研究費補助金  

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